Lysine

lysine acetyltransferase 2A ; Homo sapiens







54 Article(s)
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1 34654054 KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia. 2022 Jan 11 2
2 32841743 Catalysis by protein acetyltransferase Gcn5. 2021 Feb 1
3 32890768 The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module. 2021 Feb 2
4 33279621 Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance. 2021 Apr 1 1
5 33562796 The Histone Acetyltransferase GCN5 and the Associated Coactivators ADA2: From Evolution of the SAGA Complex to the Biological Roles in Plants. 2021 Feb 5 2
6 33854041 Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis. 2021 Apr 14 1
7 34331108 Repurposing proscillaridin A in combination with decitabine against embryonal rhabdomyosarcoma RD cells. 2021 Nov 2
8 34877957 Amide-derived lysine analogues as substrates and inhibitors of histone lysine methyltransferases and acetyltransferases. 2021 Dec 22 1
9 31320749 The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α. 2020 Feb 1
10 32747680 Effect of lysine side chain length on histone lysine acetyltransferase catalysis. 2020 Aug 3 1
11 31527837 DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription. 2019 Oct 1
12 29555684 Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5. 2018 May 11 6
13 29773900 C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. 2018 Aug 1
14 28300060 H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. 2017 Mar 16 1
15 28424240 The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation. 2017 May 15 1
16 28426094 SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. 2017 Mar 17 1
17 28854355 UV-Induced RPA1 Acetylation Promotes Nucleotide Excision Repair. 2017 Aug 29 1
18 29211711 KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase. 2017 Dec 14 1
19 27005833 Acetylation of C/EBPα inhibits its granulopoietic function. 2016 Mar 23 1
20 27216891 GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment. 2016 May 24 2
21 27377381 Structural basis for acyl-group discrimination by human Gcn5L2. 2016 Jul 2
22 26401015 Nucleosome competition reveals processive acetylation by the SAGA HAT module. 2015 Oct 6 1
23 26468280 Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5. 2015 Nov 27 1
24 23437046 Quantitating the specificity and selectivity of Gcn5-mediated acetylation of histone H3. 2013 1
25 23760262 Histone deacetylase 3 regulates cyclin A stability. 2013 Jul 19 1
26 22574209 Investigation of the acetylation mechanism by GCN5 histone acetyltransferase. 2012 1
27 23022381 The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status. 2012 Nov 9 1
28 20972224 GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage. 2011 Mar 1
29 21367571 Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells. 2011 Jun 4
30 21756203 Epigenetic modulation of PGC-1α activity by GCN5 inhibitors: WO2010007085. 2011 Oct 2
31 21900231 Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation. 2011 Oct 21 1
32 22001918 Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase. 2011 Oct 28 1
33 19940161 PGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy. 2010 Jan 22 2
34 20074040 Acetylation of cyclin A: a new cell cycle regulatory mechanism. 2010 Feb 4
35 20188666 A role for Gcn5 in replication-coupled nucleosome assembly. 2010 Feb 26 1
36 20226045 GCN5-dependent acetylation of HIV-1 integrase enhances viral integration. 2010 Mar 12 3
37 20621284 Histone acetylation, acetyltransferases, and ataxia--alteration of histone acetylation and chromatin dynamics is implicated in the pathogenesis of polyglutamine-expansion disorders. 2010 1
38 20699646 Roles for Gcn5 in promoting nucleosome assembly and maintaining genome integrity. 2010 Aug 1 1
39 19343071 Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle. 2009 Apr 1
40 19491097 GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. 2009 Jul 24 2
41 18250157 Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription. 2008 Apr 2
42 18358708 C/EBPs: recipients of extracellular signals through proteome modulation. 2008 Apr 1
43 18480452 CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. 2008 Jul 1
44 18809572 Acetylation of Rsc4p by Gcn5p is essential in the absence of histone H3 acetylation. 2008 Dec 1
45 17301242 Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5. 2007 Feb 20 1
46 14661947 Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. 2003 Dec 16 4
47 11850414 Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. 2002 Apr 5 1
48 11994311 Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases. 2002 Jul 26 1
49 12039950 Site-specific loss of acetylation upon phosphorylation of histone H3. 2002 Aug 16 2
50 12391296 Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor. 2002 Oct 29 1