Nucleosides

5'-nucleotidase, cytosolic II ; Homo sapiens







22 Article(s)
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1 32970317 Enhanced migration of breast and lung cancer cells deficient for cN-II and CD73 via COX-2/PGE2/AKT axis regulation. 2021 Feb 1
2 31778791 FMS-like tyrosine kinase 3 (FLT3) modulates key enzymes of nucleotide metabolism implicated in cytarabine responsiveness in pediatric acute leukemia. 2020 Jan 1
3 30798051 Lead optimization and biological evaluation of fragment-based cN-II inhibitors. 2019 Apr 15 3
4 27906612 Stably transfected adherent cancer cell models with decreased expression of 5'-nucleotidase cN-II. 2016 Dec 1
5 25656700 The purine analog fludarabine acts as a cytosolic 5'-nucleotidase II inhibitor. 2015 Mar 15 1
6 25998135 Determination of the enzymatic activity of cytosolic 5'-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models. 2015 Jul 1
7 26079827 Cell proliferation and drug sensitivity of human glioblastoma cells are altered by the stable modulation of cytosolic 5'-nucleotidase II. 2015 Aug 1
8 26462774 [NT5C2 expression in children with acute leukemia and its clinical significance]. 2015 Sep 1
9 24607586 Structure-activity relationships of β-hydroxyphosphonate nucleoside analogues as cytosolic 5'-nucleotidase II potential inhibitors: synthesis, in vitro evaluation and molecular modeling studies. 2014 Apr 22 2
10 23220537 Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening. 2013 Feb 15 1
11 23377281 Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. 2013 Mar 1
12 23992314 Therapeutic perspectives for cN-II in cancer. 2013 1
13 21712425 Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. 2011 Oct 1
14 22174667 Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues. 2011 Dec 1
15 20205377 Ag(+)-mediated assembly of 5'-guanosine monophosphate. 2010 Apr 1 1
16 21029378 Active and regulatory sites of cytosolic 5'-nucleotidase. 2010 Dec 1
17 16629121 F-ara-AMP is a substrate of cytoplasmic 5'-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation. 2006 Mar 1
18 18404470 Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II). 2006 Nov 2
19 15946667 Regulation and activity of cytosolic 5'-nucleotidase II. A bifunctional allosteric enzyme of the Haloacid Dehalogenase superfamily involved in cellular metabolism. 2005 Jun 20 2
20 12907246 Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy. 2003 Aug 1 1
21 12916861 Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies. 2003 Jul 1
22 87197 Inhibition of human lung cyclic GMP and cyclic AMP phosphodiesterases by certain nucleosides, nucleotides, and pharmacological phosphodiesterase inhibitors. 1979 Apr 1 1