Sulfhydryl Compounds

peroxiredoxin 5 ; Homo sapiens







37 Article(s)
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Pub. Year
#Total Relationships
1 34541904 Thiol-Based Antioxidants and the Epithelial/Mesenchymal Transition in Cancer. 2022 May 1
2 34656698 Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells. 2021 Dec 1
3 34923938 Oridonin induces oxidative stress-mediated cancer cells apoptosis via targeting thioredoxin reductase. 2021 Dec 17 1
4 31521661 A review on the druggability of a thiol-based enzymatic antioxidant thioredoxin reductase for treating filariasis and other parasitic infections. 2020 Jan 1 4
5 32033229 Arsenic Toxicity: Molecular Targets and Therapeutic Agents. 2020 Feb 4 1
6 32961182 Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era. 2020 Dec 15 1
7 33238608 Antiproliferative Homoleptic and Heteroleptic Phosphino Silver(I) Complexes: Effect of Ligand Combination on Their Biological Mechanism of Action. 2020 Nov 23 1
8 30401714 Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis. 2019 Jan 1 1
9 31801208 In Vitro Assessment of the Efficacy of a Macrocyclic Chelator in Reversing Methylmercury Toxicity. 2019 Nov 30 2
10 29775743 Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium. 2018 Nov 1 2
11 27667125 The role of electrostatics in TrxR electron transfer mechanism: A computational approach. 2016 Dec 1
12 25868756 Chemical biology of anticancer gold(III) and gold(I) complexes. 2015 Dec 21 1
13 24351040 Highly selective off-on fluorescent probe for imaging thioredoxin reductase in living cells. 2014 Jan 8 1
14 24374250 Activity assays of mammalian thioredoxin and thioredoxin reductase: fluorescent disulfide substrates, mechanisms, and use with tissue samples. 2014 Mar 15 1
15 24422500 Selenium as an electron acceptor during the catalytic mechanism of thioredoxin reductase. 2014 Feb 4 2
16 24661219 Acetaminophen reactive intermediates target hepatic thioredoxin reductase. 2014 May 19 1
17 25036792 Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells. 2014 Sep 12 2
18 25289458 Interaction of adenanthin with glutathione and thiol enzymes: selectivity for thioredoxin reductase and inhibition of peroxiredoxin recycling. 2014 Dec 1
19 23121505 Is oxidized thioredoxin a major trigger for cysteine oxidation? Clues from a redox proteomics approach. 2013 May 1 3
20 23149817 Evaluation of arene ruthenium(II) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules. 2013 Feb 7 1
21 23223577 Thioredoxin and thioredoxin reductase control tissue factor activity by thiol redox-dependent mechanism. 2013 Feb 1 1
22 23396001 Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. 2013 May 1
23 22003958 Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression. 2012 Jul 1
24 20512387 Polyamine metabolism in Leishmania: from arginine to trypanothione. 2011 Feb 1
25 21812108 The effects of acrolein on the thioredoxin system: implications for redox-sensitive signaling. 2011 Sep 2
26 20345183 Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells. 2010 Jun 21 1
27 21072382 Cysteine proteases as targets for metal-based drugs. 2010 Jun 1
28 18489898 The crystal structures of oxidized forms of human peroxiredoxin 5 with an intramolecular disulfide bond confirm the proposed enzymatic mechanism for atypical 2-Cys peroxiredoxins. 2008 Sep 1 2
29 16438969 Characterization of human thioredoxin-like-1: potential involvement in the cellular response against glucose deprivation. 2006 Feb 6 2
30 16520229 Antiglioma activity of 2,2':6',2"-terpyridineplatinum(II) complexes in a rat model--effects on cellular redox metabolism. 2006 Mar 1 2
31 17056271 On the potential of thioredoxin reductase inhibitors for cancer therapy. 2006 Dec 3
32 16158536 Expression and distribution of thioredoxin and thioredoxin reductase in human nasal mucosa and nasal polyp. 2005 Aug 1
33 12963029 A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines. 2003 Sep 26 1
34 12204825 Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. 2002 Sep 1
35 11728801 Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. 2001 Dec 1 1
36 10996515 Antioxidant enzymes; possible mechanism of gold compound treatment in rheumatoid arthritis. 2000 Sep 1
37 10232828 Nitroxide metabolism in the human keratinocyte cell line HaCaT. 1999 Apr 1