Cysteine

peroxiredoxin 5 ; Homo sapiens







46 Article(s)
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1 34579115 Selenium, a Micronutrient That Modulates Cardiovascular Health via Redox Enzymology. 2021 Sep 17 1
2 34943005 Role of the Redox State of Human Peroxiredoxin-5 on Its TLR4-Activating DAMP Function. 2021 Nov 27 2
3 33060708 Structural basis of peroxidase catalytic cycle of human Prdx6. 2020 Oct 15 1
4 30997926 Modelling the Inhibition of Selenoproteins by Small Molecules Using Cysteine and Selenocysteine Derivatives. 2019 Jul 2 1
5 31375973 A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification. 2019 Nov 1
6 29072450 Ebselen: Mechanisms of Glutamate Dehydrogenase and Glutaminase Enzyme Inhibition. 2017 Dec 15 1
7 25306263 An investigation into the interactions of gold nanoparticles and anti-arthritic drugs with macrophages, and their reactivity towards thioredoxin reductase. 2015 Jan 2
8 26451472 Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction. 2015 Nov 16 1
9 24407164 Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase. 2014 Apr 2
10 24422500 Selenium as an electron acceptor during the catalytic mechanism of thioredoxin reductase. 2014 Feb 4 2
11 24624337 Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine. 2014 1
12 24661219 Acetaminophen reactive intermediates target hepatic thioredoxin reductase. 2014 May 19 2
13 24844612 A furanyl acryl conjugated coumarin as an efficient inhibitor and a highly selective off-on fluorescent probe for covalent labelling of thioredoxin reductase. 2014 Jul 7 1
14 24867309 Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase. 2014 Jun 26 1
15 24999795 Why selenocysteine replaces cysteine in thioredoxin reductase: a radical hypothesis. 2014 Aug 5 1
16 25184942 Deconstructing the catalytic efficiency of peroxiredoxin-5 peroxidatic cysteine. 2014 Sep 30 4
17 23223577 Thioredoxin and thioredoxin reductase control tissue factor activity by thiol redox-dependent mechanism. 2013 Feb 1 2
18 21443269 Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes. 2011 May 16 1
19 20305821 Discovery of fragment molecules that bind the human peroxiredoxin 5 active site. 2010 Mar 17 1
20 20345183 Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells. 2010 Jun 21 1
21 20457604 The selenium-independent inherent pro-oxidant NADPH oxidase activity of mammalian thioredoxin reductase and its selenium-dependent direct peroxidase activities. 2010 Jul 9 10
22 20951799 Molecular bases of thioredoxin and thioredoxin reductase-mediated prooxidant actions of (-)-epigallocatechin-3-gallate. 2010 Dec 15 3
23 18202017 2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation. 2008 Jan 1
24 18501718 Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates. 2008 Aug 15 1
25 18685195 Inhibition of thioredoxin reductase by curcumin analogs. 2008 Aug 1
26 16464088 Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. 2006 Feb 15 7
27 16618767 Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity. 2006 Apr 15 1
28 16780799 Characterization of mitochondrial thioredoxin reductase from C. elegans. 2006 Aug 4 1
29 16863998 Studies of an active site mutant of the selenoprotein thioredoxin reductase: the Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the mammalian enzyme. 2006 Aug 15 2
30 15046979 Crystal structure of a dimeric oxidized form of human peroxiredoxin 5. 2004 Apr 9 2
31 15184375 Cysteine oxidation of tau and microtubule-associated protein-2 by peroxynitrite: modulation of microtubule assembly kinetics by the thioredoxin reductase system. 2004 Aug 13 1
32 15280035 Human peroxiredoxin 5 is a peroxynitrite reductase. 2004 Jul 30 2
33 11832487 Glutaredoxin-dependent peroxiredoxin from poplar: protein-protein interaction and catalytic mechanism. 2002 Apr 19 1
34 12169016 Plant thioredoxins: the multiplicity conundrum. 2002 Jun 1
35 12214272 Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. 2002 Sep 12 1
36 11134895 Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity. 2001 Jan 1 1
37 11331281 Regulation of interferon and retinoic acid-induced cell death activation through thioredoxin reductase. 2001 Jul 6 1
38 11518528 Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5 A resolution. 2001 Aug 24 1
39 10751410 Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate. 2000 Jul 7 11
40 10906242 Identification of proteins containing cysteine residues that are sensitive to oxidation by hydrogen peroxide at neutral pH. 2000 Aug 1 1
41 9556556 Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue. 1998 May 1 3
42 9671710 Human thioredoxin reductase from HeLa cells: selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin. 1998 Jul 21 4
43 9685351 Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. 1998 Aug 7 1
44 8650234 Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene. 1996 Jun 11 4
45 7589432 Cloning and sequencing of a human thioredoxin reductase. 1995 Oct 2 1
46 8484715 Activation of oxidized cysteine proteinases by thioredoxin-mediated reduction in vitro. 1993 Apr 15 1