| 1 |
33851518 | Rifampicin induces the bone form of alkaline phosphatase in humans. | 2022 Jan |
2 |
| 2 |
29424600 | Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats. | 2019 Feb |
1 |
| 3 |
29548889 | Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats. | 2018 May 1 |
6 |
| 4 |
28825834 | Combining Genomics To Identify the Pathways of Post-Transcriptional Nongenotoxic Signaling and Energy Homeostasis in Livers of Rats Treated with the Pregnane X Receptor Agonist, Pregnenolone Carbonitrile. | 2017 Oct 6 |
1 |
| 5 |
23588309 | Pregnane X receptor agonists impair postprandial glucose tolerance. | 2013 Jun |
2 |
| 6 |
21402137 | 3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition. | 2011 May 30 |
2 |
| 7 |
20048746 | Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells. | 2010 Jan |
2 |
| 8 |
19432992 | Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics. | 2009 May 11 |
1 |
| 9 |
18349876 | Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier. | 2008 Jun |
4 |
| 10 |
16997903 | Identification of genes controlled by the pregnane X receptor by microarray analysis of mRNAs from pregnenolone 16alpha-carbonitrile-treated rats. | 2006 Dec |
1 |
| 11 |
15367577 | Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter. | 2005 Feb |
2 |
| 12 |
15595924 | Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms. | 2005 May 1 |
2 |
| 13 |
15596064 | Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital. | 2005 Feb |
2 |
| 14 |
15826607 | Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23. | 2005 May 1 |
1 |
| 15 |
11854146 | Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver. | 2002 Mar |
3 |
| 16 |
11901222 | Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor. | 2002 Apr |
5 |
| 17 |
12011477 | Regulation of rat multidrug resistance protein 2 by classes of prototypical microsomal enzyme inducers that activate distinct transcription pathways. | 2002 Jun |
2 |
| 18 |
12034349 | Ectopic expression of MHC class II genes (RT1.B(I) beta/alpha) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists pregnenolone 16 alpha-carbonitrile and dexamethasone. | 2002 Jun 7 |
2 |
| 19 |
12167565 | Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes. | 2002 Sep |
1 |
| 20 |
11336976 | Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics. | 2001 May 16 |
1 |
| 21 |
10772631 | Rabbit pregnane X receptor is activated by rifampicin. | 2000 May |
1 |
| 22 |
11043605 | Identification by differential display of the IF1 inhibitor peptide of ATP synthase/ATPase as a gene inducible in rat liver by pregnenolone 16alpha-carbonitrile. | 2000 Sep 1 |
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