pifithrin

heat shock protein family A (Hsp70) member 4 ; Homo sapiens







13 Article(s)
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1 33835030 PES inhibits human-inducible Hsp70 by covalent targeting of cysteine residues in the substrate-binding domain. 2021 Jan-Jun 1
2 29899847 Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity. 2018 May 25 1
3 30066840 Inducible HSP70 antagonizes cisplatin‑induced cell apoptosis through inhibition of the MAPK signaling pathway in HGC‑27 cells. 2018 Oct 1
4 29135937 Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters. 2017 Nov 14 1
5 26534988 Threonine-408 Regulates the Stability of Human Pregnane X Receptor through Its Phosphorylation and the CHIP/Chaperone-Autophagy Pathway. 2016 Jan 1
6 27395830 Functional inhibition of Hsp70 by Pifithrin-μ switches Gambogic acid induced caspase dependent cell death to caspase independent cell death in human bladder cancer cells. 2016 Nov 3
7 27455212 Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells. 2016 Jul 21 2
8 27869678 Correction: Griffith, D.M., et al. Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells. Molecules 2016, 21, 949. 2016 Nov 17 1
9 28405636 When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters. 2016 Dec 30 1
10 23371857 The HSP70 and autophagy inhibitor pifithrin-μ enhances the antitumor effects of TRAIL on human pancreatic cancer. 2013 Apr 1
11 21755988 Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft. 2011 Aug 23 2
12 22829184 Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia. 2011 Jul 2
13 15145929 Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. 2004 Jul 16 1