Sulfasalazine

nuclear factor kappa B subunit 1 ; Homo sapiens







50 Article(s)
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1 33289342 Sulfasalazine synergistically enhances the inhibitory effects of imatinib against hepatocellular carcinoma (HCC) cells by targeting NFκB, BCR/ABL, and PI3K/AKT signaling pathway-related proteins. 2021 Mar 1
2 31269957 Cathepsin L-induced galectin-1 may act as a proangiogenic factor in the metastasis of high-grade serous carcinoma. 2019 Jul 3 1
3 25043904 Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation. 2014 Dec 2
4 23350962 The nuclear factor-κB pathway down-regulates expression of the NKG2D ligand H60a in vitro: implications for use of nuclear factor-κB inhibitors in cancer therapy. 2013 Jun 1
5 23965971 UVB-stimulated TNFα release from human melanocyte and melanoma cells is mediated by p38 MAPK. 2013 Aug 19 1
6 22323467 NF-κB is the transcription factor for FGF-2 that causes endothelial mesenchymal transformation in cornea. 2012 Mar 21 1
7 22496207 Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease. 2012 Apr 1
8 21889336 Oleanane-type triterpene saponins from the bark of Aralia elata and their NF-κB inhibition and PPAR activation signal pathway. 2011 Oct 15 1
9 19693652 Induction of RIP-2 kinase by proinflammatory cytokines is mediated via NF-kappaB signaling pathways and involves a novel feed-forward regulatory mechanism. 2010 Jan 1
10 19859796 Sulfasalazine induces apoptosis of HBx-expressing cells in an NF-kappaB-independent manner. 2010 Feb 3
11 20103633 NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells. 2010 Feb 1 3
12 20884048 NFκB-dependent increase of kynurenine pathway activity in human placenta: inhibition by sulfasalazine. 2010 Nov 4
13 19723887 Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer. 2009 Sep 1
14 18997870 Memory extinction entails the inhibition of the transcription factor NF-kappaB. 2008 2
15 17440102 Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL. 2007 Apr 15 4
16 16448552 A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]. 2006 Jan 31 1
17 16614379 Differential involvement of nuclear factor-kappaB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA. 2006 Apr 1
18 16973133 Can NF-kappaB be a target for novel and efficient anti-cancer agents? 2006 Oct 30 1
19 15564333 Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. 2005 Mar 2
20 15687229 Activation of the transcription factor NF-kappaB by retrieval is required for long-term memory reconsolidation. 2005 Jan-Feb 1
21 15746563 Translocation of nuclear factor-kappaB on corneal epithelial cells induced by ultraviolet B irradiation. 2005 Mar-Apr 1
22 15761248 NF-kappaB decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis. 2005 Feb 28 1
23 15811753 Cellular death mediated by nuclear factor kappa B (NF-kappaB) translocation in cultured human lens epithelial cells after ultraviolet-B irradiation. 2005 Mar 2
24 15955209 Sulfasalazine inhibits activation of nuclear factor-kappaB in patients with ulcerative colitis. 2005 Jul 3
25 14687604 N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor. 2004 May 2
26 15203565 Secretion of interleukin-8 by human-derived cell lines infected with Mycobacterium bovis. 2004 Feb 1
27 15243130 Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter. 2004 Oct 1
28 15280021 Gliadin stimulates human monocytes to production of IL-8 and TNF-alpha through a mechanism involving NF-kappaB. 2004 Jul 30 1
29 15328202 In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas. 2004 Aug 15 2
30 15494508 NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes. 2004 Nov 1 2
31 12631585 Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. 2003 Mar 1
32 12761494 Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. 2003 May 22 1
33 12934082 NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells. 2003 Sep 1
34 11786414 Nuclear factor-kappa B activation in human testicular apoptosis. 2002 Jan 3
35 11830551 Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines. 2002 Feb 1 1
36 11901219 Involvement of activator protein-1 in transcriptional regulation of the human mu-opioid receptor gene. 2002 Apr 1
37 12054592 Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells. 2002 Apr 26 3
38 12065617 Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. 2002 Jun 1
39 12104053 NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival. 2002 Oct 8 2
40 12135912 Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro. 2002 Aug 1
41 11314019 Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. 2001 Feb 15 1
42 11444836 Nuclear factor-kappab blockade attenuates but does not abrogate lipopolysaccharide-dependent tumor necrosis factor-alpha biosynthesis in alveolar epithelial cells. 2001 Jul 13 3
43 10777712 The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting. 2000 Apr 29 1
44 10975857 Role of NF-kappa B in cytokine production induced from human airway epithelial cells by rhinovirus infection. 2000 Sep 15 2
45 11054378 Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. 2000 Nov 6
46 11063988 Failure to activate NF-kappaB promotes apoptosis of retinal ganglion cells following optic nerve transection. 2000 Nov 10 3
47 10402163 Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis. 1999 Jun 1
48 10572418 [Present states of development in new drugs and treatment of inflammatory bowel disease]. 1999 Nov 1
49 10598732 Sulfasalazine inhibits reperfusion injury and prolongs allograft survival in rat cardiac transplants. 1999 Nov 1
50 9486988 Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. 1998 Mar 1 6