trichostatin A

nuclear factor kappa B subunit 1 ; Homo sapiens







32 Article(s)
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1 35598597 Tanshinone IIA inhibits tissue factor expression induced by thrombin in human umbilical vein endothelial cells via PAR-1 and p38 MAPK signaling pathway. 2022 May 20 2
2 33335577 Regulation of dimethylarginine dimethylaminohydrolase 2 expression by NF-κB acetylation. 2021 Feb 3
3 33671042 IL-33 Is Involved in the Anti-Inflammatory Effects of Butyrate and Propionate on TNFα-Activated Endothelial Cells. 2021 Feb 28 1
4 31950542 HDAC1 and HDAC2 regulate anti-inflammatory effects of anesthetic isoflurane in human monocytes. 2020 Apr 1
5 30655811 Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A. 2019 Jan 8
6 31226340 Age-related macular degeneration (AMD) mitochondria modulate epigenetic mechanisms in retinal pigment epithelial cells. 2019 Dec 2
7 25941940 HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes. 2015 1
8 26579129 Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases. 2015 1
9 24562770 mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms. 2014 Apr 1
10 23297421 Regulation of GTP-binding protein (Gαs) expression in human myometrial cells: a role for tumor necrosis factor in modulating Gαs promoter acetylation by transcriptional complexes. 2013 Mar 1 1
11 23555753 Enhancement of inflammatory protein expression and nuclear factor Κb (NF-Κb) activity by trichostatin A (TSA) in OP9 preadipocytes. 2013 5
12 21953341 Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay. 2012 Mar 1
13 21983014 Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1. 2012 Feb 1
14 22781708 ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-κB-dependent and Notch-independent mechanism. 2012 Sep 4 6
15 20130413 Constitutive and tumor necrosis factor-alpha-stimulated activation of nuclear factor-kappaB in immortalized endometriotic cells and their suppression by trichostatin A. 2010 2
16 18064564 Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. 2008 Nov 2
17 18652825 Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. 2008 Oct 1 3
18 18669446 Interleukin-8 expression is regulated by histone deacetylases through the nuclear factor-kappaB pathway in breast cancer. 2008 Nov 1
19 19083427 Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. 2008 May 3
20 19140318 [NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. 2008 Nov-Dec 3
21 17250678 Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. 2007 Jun 6
22 17586512 Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium. 2007 Dec 2
23 16581766 Permissive effects of oxygen on cyclic AMP and interleukin-1 stimulation of surfactant protein A gene expression are mediated by epigenetic mechanisms. 2006 Apr 1
24 16683270 NF-kappaB activation upregulates fibroblast growth factor 8 expression in prostate cancer cells. 2006 Aug 1 1
25 16904634 Histone deacetylase inhibitor trichostatin A and proteasome inhibitor PS-341 synergistically induce apoptosis in pancreatic cancer cells. 2006 Oct 6 1
26 15950952 HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. 2005 Aug 1 2
27 16026644 Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma. 2005 Jul 1
28 15313420 Regulation at multiple levels of NF-kappaB-mediated transactivation by protein acetylation. 2004 Sep 15 1
29 12917341 Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. 2003 Sep 4
30 12368351 Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies. 2002 Nov 2
31 11564889 The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. 2001 Oct 6
32 10734024 The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. 2000 Apr 1