GW9508

free fatty acid receptor 1 ; Homo sapiens







26 Article(s)
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1 35061031 GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression. 2022 Apr 1 1
2 33715419 In silico design of bioisosteric modifications of drugs for the treatment of diabetes. 2021 Apr 1
3 32347098 Retraction of "GPR40 Agonist GW9508 Ameliorates Oxidized LDL-Induced Endothelial Dysfunction via the AMPK/CREB/PGC-1α Pathway". 2020 Sep 21 3
4 32606604 Activation of GPR40 Suppresses AGE-Induced Reduction of Type II Collagen and Aggrecan in Human SW1353 Chondrocytes. 2020 5
5 33133087 The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections. 2020 2
6 31129422 Pharmacological stimulation of G-protein coupled receptor 40 alleviates cytokine-induced epithelial barrier disruption in airway epithelial Calu-3 cells. 2019 Aug 3
7 31214048 Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter. 2019 1
8 29321392 [The role of brain n-3 fatty acids-GPR40/FFAR1 signaling in pain]. 2018 2
9 29750897 Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells. 2018 Aug 1 1
10 29777058 GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells. 2018 Jul 6 4
11 29913106 GPR40 receptor activation promotes tight junction assembly in airway epithelial cells via AMPK-dependent mechanisms. 2018 4
12 28154332 A New Pain Regulatory System via the Brain Long Chain Fatty Acid Receptor GPR40/FFA1 Signal. 2017 1
13 28159555 Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells. 2017 Mar 11 2
14 26331585 Negative effects of G-protein-coupled free fatty acid receptor GPR40 on cell migration and invasion in fibrosarcoma HT1080 cells. 2016 Nov 1
15 26869446 Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. 2016 May 1
16 27121981 GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway. 2016 Apr 28 1
17 25447053 Tumor necrosis factor α decreases glucagon-like peptide-2 expression by up-regulating G-protein-coupled receptor 120 in Crohn disease. 2015 Jan 1
18 26342087 Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle. 2015 Nov 1 1
19 25008074 Activation of free fatty acid receptor 1 improves hepatic steatosis through a p38-dependent pathway. 2014 Oct 2
20 23341496 Multiple mechanisms of GW-9508, a selective G protein-coupled receptor 40 agonist, in the regulation of glucose homeostasis and insulin sensitivity. 2013 Mar 15 4
21 21334233 Insight into analysis of interactions of GW9508 to wild-type and H86F and H137F GPR40: a combined QM/MM study and pharmacophore modeling. 2011 Apr 2
22 21570468 Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. 2011 Aug 1
23 21575602 Oleic acid induces intracellular calcium mobilization, MAPK phosphorylation, superoxide production and granule release in bovine neutrophils. 2011 Jun 3 1
24 21593768 A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation. 2011 Aug 3
25 17699519 Identification of residues important for agonist recognition and activation in GPR40. 2007 Oct 5 1
26 16702987 Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. 2006 Jul 1