| 1 |
35455942 | SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells. | 2022 Apr 8 |
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| 2 |
35503397 | Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer. | 2022 May 3 |
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| 3 |
34147559 | The ribosomal protein eL21 interacts with the protein lysine methyltransferase SMYD2 and regulates its steady state levels. | 2021 Aug |
2 |
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33011288 | Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors. | 2020 Nov 15 |
5 |
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31370883 | Histone methyltransferase SMYD2: ubiquitous regulator of disease. | 2019 Aug 1 |
2 |
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31693890 | Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis. | 2019 Nov 5 |
3 |
| 7 |
30190324 | A motif in HSP90 and P23 that links molecular chaperones to efficient estrogen receptor α methylation by the lysine methyltransferase SMYD2. | 2018 Oct 19 |
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| 8 |
28370702 | Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells. | 2017 Jun |
2 |
| 9 |
28494238 | SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. | 2017 May 10 |
1 |
| 10 |
28915556 | Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling. | 2017 Aug 22 |
1 |
| 11 |
26750096 | Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based Proteomics. | 2016 Mar |
2 |
| 12 |
27075367 | Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2. | 2016 May 26 |
1 |
| 13 |
25583990 | The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production. | 2015 Feb 27 |
2 |
| 14 |
25825497 | LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. | 2015 May 29 |
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| 15 |
25925379 | Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. | 2015 Apr |
3 |
| 16 |
24594358 | Structural insights into estrogen receptor α methylation by histone methyltransferase SMYD2, a cellular event implicated in estrogen signaling regulation. | 2014 Oct 9 |
2 |
| 17 |
24726141 | The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells. | 2014 Mar |
1 |
| 18 |
24880080 | SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation. | 2014 Aug 28 |
1 |
| 19 |
25014164 | Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis. | 2014 Nov |
2 |
| 20 |
24101509 | Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation. | 2013 Oct 22 |
2 |
| 21 |
22241783 | Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization. | 2012 Jan 15 |
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| 22 |
22787429 | RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. | 2012 Jun |
4 |
| 23 |
21678921 | Biochemical characterization of human SET and MYND domain-containing protein 2 methyltransferase. | 2011 Jul 26 |
2 |
| 24 |
21724641 | Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins. | 2011 Oct |
9 |
| 25 |
21880715 | Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation. | 2011 Nov 4 |
4 |
| 26 |
20870719 | Methylation of the retinoblastoma tumor suppressor by SMYD2. | 2010 Nov 26 |
1 |
| 27 |
18581285 | Protein methylation: a new mechanism of p53 tumor suppressor regulation. | 2008 Sep |
2 |
| 28 |
16805913 | Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. | 2006 Jun 28 |
1 |
| 29 |
17108971 | Repression of p53 activity by Smyd2-mediated methylation. | 2006 Nov 30 |
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