| 1 |
35042744 | Hypoxia-Inducible Factors in Cancer. | 2022 Jan 15 |
1 |
| 2 |
35415275 | Role of prolyl hydroxylase domain proteins in bone metabolism. | 2022 Mar |
2 |
| 3 |
33550096 | Alternative regulation of HIF-1α stability through Phosphorylation on Ser451. | 2021 Mar 19 |
1 |
| 4 |
31618435 | Prolyl Hydroxylase Inhibition Mitigates Pouchitis. | 2020 Jan 6 |
1 |
| 5 |
31944416 | Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients. | 2020 Mar |
1 |
| 6 |
30700584 | Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes. | 2019 Mar 1 |
1 |
| 7 |
31500697 | Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates. | 2019 Sep 10 |
2 |
| 8 |
29259012 | FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes. | 2018 Mar 1 |
2 |
| 9 |
29330785 | Genetic Knockdown and Pharmacologic Inhibition of Hypoxia-Inducible Factor (HIF) Hydroxylases. | 2018 |
2 |
| 10 |
29435987 | The PHD1 oxygen sensor in health and disease. | 2018 Sep |
1 |
| 11 |
29580991 | Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH. | 2018 May 15 |
1 |
| 12 |
30411685 | Role of HIF-1 in Cancer Progression: Novel Insights. A Review. | 2018 |
1 |
| 13 |
26644182 | CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. | 2016 Jan 1 |
1 |
| 14 |
26735018 | An ID2-dependent mechanism for VHL inactivation in cancer. | 2016 Jan 14 |
2 |
| 15 |
26921340 | Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. | 2016 Apr 15 |
1 |
| 16 |
27502280 | Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases. | 2016 Sep 23 |
1 |
| 17 |
27581016 | Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL). | 2016 |
2 |
| 18 |
25809665 | Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing. | 2015 Jun |
1 |
| 19 |
26296657 | pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation. | 2015 Nov |
1 |
| 20 |
26492917 | EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. | 2015 Dec 2 |
2 |
| 21 |
23225569 | Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing. | 2013 Jun 15 |
1 |
| 22 |
23380539 | The regulation, localization, and functions of oxygen-sensing prolyl hydroxylase PHD3. | 2013 Apr |
1 |
| 23 |
23932902 | PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. | 2013 Aug 26 |
2 |
| 24 |
22395314 | Molecular oxygen sensing: implications for visceral surgery. | 2012 Apr |
1 |
| 25 |
20980551 | Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets. | 2011 Feb |
1 |
| 26 |
21951999 | PHD1 interacts with ATF4 and negatively regulates its transcriptional activity without prolyl hydroxylation. | 2011 Dec 10 |
1 |
| 27 |
20156434 | Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth. | 2010 Apr 15 |
1 |
| 28 |
20205712 | Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software. | 2010 Mar 5 |
1 |
| 29 |
18952043 | Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology. | 2009 Jan 15 |
1 |
| 30 |
19165233 | Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease. | 2009 Feb |
6 |
| 31 |
19546213 | Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. | 2009 Aug 21 |
1 |
| 32 |
19631610 | Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2. | 2009 Oct 2 |
1 |
| 33 |
19756382 | Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. | 2009 Nov |
1 |
| 34 |
18773095 | Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response. | 2008 Sep 5 |
3 |
| 35 |
18927305 | Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH Is associated with tumor aggressiveness in pancreatic endocrine tumors. | 2008 Oct 15 |
2 |
| 36 |
16509823 | Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation. | 2006 Jul 1 |
2 |
| 37 |
16565084 | Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. | 2006 Jun 2 |
1 |
| 38 |
16611863 | Dynamic HIF1A regulation during human placental development. | 2006 Jul |
1 |
| 39 |
16686427 | Regulation of HIF: prolyl hydroxylases. | 2006 |
2 |
| 40 |
17002676 | Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. | 2006 Oct |
1 |
| 41 |
15563275 | Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element. | 2005 May 1 |
1 |
| 42 |
15178343 | Hypoxia-dependent regulation of PHD1: cloning and characterization of the human PHD1/EGLN2 gene promoter. | 2004 Jun 4 |
2 |
| 43 |
15474027 | Determination and comparison of specific activity of the HIF-prolyl hydroxylases. | 2004 Oct 8 |
1 |
| 44 |
12615973 | Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing. | 2003 Apr 1 |
3 |
| 45 |
12234095 | Mammalian EGLN genes have distinct patterns of mRNA expression and regulation. | 2002 |
1 |