Guanosine Triphosphate

RAB3A, member RAS oncogene family ; Homo sapiens







62 Article(s)
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1 29289693 Manganese-induced alpha-synuclein overexpression impairs synaptic vesicle fusion by disrupting the Rab3 cycle in primary cultured neurons. 2018 Mar 15 3
2 30237463 O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma. 2018 Sep 20 3
3 28057568 Localization of Rab3A-binding site on C2A domain of synaptotagmin I to reveal its regulatory mechanism. 2017 Mar 1
4 28900422 Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles. 2017 1
5 25713146 ADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation. 2015 Apr 10 1
6 24652202 3D structure generation, virtual screening and docking of human Ras-associated binding (Rab3A) protein involved in tumourigenesis. 2014 Jun 1
7 25053757 GTP-bound Rab3A exhibits consecutive positive and negative roles during human sperm dense-core granule exocytosis. 2014 Aug 2
8 23344955 α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity. 2013 Mar 15 2
9 22609963 Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphate. 2012 Sep 1
10 22753498 Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis. 2012 Jul 24 2
11 21689256 Involvement of Rab3A in vesicle priming during exocytosis: interaction with Munc13-1 and Munc18-1. 2011 Oct 1
12 18798275 Role for Rab3a in oligodendrocyte morphological differentiation. 2009 Feb 4
13 19077034 Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. 2009 Jan 1
14 19170188 The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia. 2009 Nov 15 1
15 19546222 Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis. 2009 Sep 11 1
16 17625073 Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm. 2007 Dec 1
17 17637832 The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1. 2007 Jul 18 2
18 15854772 Alpha-synuclein binding to rab3a in multiple system atrophy. 2005 May 20-27 1
19 15265865 Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals. 2004 Oct 15 2
20 11853534 The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells. 2002 Mar 1 1
21 11879192 GTP binds to Rab3A in a complex with Ca2+/calmodulin. 2002 Mar 15 10
22 11906819 Prenylcysteine carboxymethyltransferase type III activity is decreased in retinoic acid-treated SH-SY5Y neuroblastoma cells. 2002 May 2
23 12526085 Phosphorylation of 46-kDa protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin. 2002 Dec 31 1
24 11278839 Rab3a binding and secretion-enhancing domains in Rim1 are separate and unique. Studies in adrenal chromaffin cells. 2001 Apr 20 1
25 11513847 Rab3a controls exocytosis in cholecystokinin-secreting cells. 2001 Aug 10 1
26 11522668 A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis. 2001 Sep 2
27 11640918 Characterization of rabphilin phosphorylation using phospho-specific antibodies. 2001 Nov 2
28 10727281 Rab3A triggers the acrosome reaction in permeabilized human spermatozoa. 2000 Apr 1
29 10954749 Calcium-triggered acrosomal exocytosis in human spermatozoa requires the coordinated activation of Rab3A and N-ethylmaleimide-sensitive factor. 2000 Aug 29 2
30 9914469 Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. 1999 Jan 1
31 10025402 Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. 1999 Feb 5 1
32 10037470 SNARE complex proteins, including the cognate pair VAMP-2 and syntaxin-4, are expressed in cultured oligodendrocytes. 1999 Mar 1
33 10196122 Structural basis of activation and GTP hydrolysis in Rab proteins. 1999 Apr 15 2
34 10512754 Dissociation of RalA from synaptic membranes by Ca2+/calmodulin. 1999 Oct 5 2
35 9417123 Involvement of Rabphilin3 in endocytosis through interaction with Rabaptin5. 1998 Jan 2 2
36 9224661 A novel function of the C-terminal lipid moieties of Rab3A small G protein implicated in Ca2+-dependent exocytosis--inhibition of interaction with GTP and reduction of this inhibition by phospholipid. 1997 Apr 10
37 8723712 Rabphilin-3A is transported with fast anterograde axonal transport and associated with synaptic vesicles. 1996 Jun 1
38 8841986 Differential expression of rab3 isoforms in oligodendrocytes and astrocytes. 1996 Aug 1 1
39 8943213 Physical and functional interaction of rabphilin-3A with alpha-actinin. 1996 Dec 13 1
40 9078389 Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis. 1996 Jul 1
41 7585614 Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens. 1995 Nov 15 2
42 7626028 Stimulation of inositol 1,4,5-trisphosphate production by peptides corresponding to the effector domain of different Rab3 isoforms and cross-linking of an effector domain peptide target. 1995 Jul 15 1
43 8521869 Rab3a, a small GTP-binding protein, undergoes fast anterograde transport but not retrograde transport in neurons. 1995 Aug 2
44 8554624 Heterotetramer formation of prenylated Rab3A with two Rabphilin-3A molecules. 1995 Dec 26 2
45 7524063 Expression of the ras-related rab3a gene in human insulinomas and normal human pancreatic islets. 1994 Jul 2
46 7524341 Effect of a Rab3A effector domain-related peptide, CCK, and EGF in permeabilized pancreatic acini. 1994 Sep 1
47 7926025 GDP/GTP exchange reaction-stimulating activity of Rabphilin-3A for Rab3A small GTP-binding protein. 1994 Oct 10 21
48 7945346 Phosphorylation of Rabphilin-3A, a putative target protein for Rab3A, by cyclic AMP-dependent protein kinase. 1994 Sep 30 10
49 7961732 Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet. 1994 Nov 11 1
50 8070588 Comparison of kinetic properties between MSS4 and Rab3A GRF GDP/GTP exchange proteins. 1994 Aug 22 3