| 1 |
34942305 | SETD8 stabilized by USP17 epigenetically activates SREBP1 pathway to drive lipogenesis and oncogenesis of ccRCC. | 2022 Feb 28 |
1 |
| 2 |
35246238 | Roles for the methyltransferase SETD8 in DNA damage repair. | 2022 Mar 4 |
2 |
| 3 |
35317899 | SET8 Inhibition Potentiates Radiotherapy by Suppressing DNA Damage Repair in Carcinomas. | 2022 Mar 20 |
1 |
| 4 |
35404465 | Distinct developmental phenotypes result from mutation of Set8/KMT5A and histone H4 lysine 20 in Drosophila melanogaster. | 2022 May 31 |
1 |
| 5 |
35449131 | KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling. | 2022 Apr 21 |
2 |
| 6 |
33565211 | Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation. | 2021 Apr 7 |
1 |
| 7 |
33574035 | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. | 2021 Apr |
1 |
| 8 |
33782381 | The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy. | 2021 Mar 29 |
1 |
| 9 |
34022460 | Histone lysine methyltransferase SET8 is a novel therapeutic target for cancer treatment. | 2021 Oct |
1 |
| 10 |
34530900 | Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma. | 2021 Sep 16 |
3 |
| 11 |
34745943 | LukS-PV Induces Apoptosis via the SET8-H4K20me1-PIK3CB Axis in Human Acute Myeloid Leukemia Cells. | 2021 |
1 |
| 12 |
34909158 | Total synthesis of nahuoic acid A via a putative biogenetic intramolecular Diels-Alder (IMDA) reaction. | 2021 Nov 24 |
1 |
| 13 |
32161353 | Downregulation of histone methyltransferase SET8 inhibits progression of hepatocellular carcinoma. | 2020 Mar 11 |
2 |
| 14 |
32178723 | The histone methyltransferase Setd8 alters the chromatin landscape and regulates the expression of key transcription factors during erythroid differentiation. | 2020 Mar 16 |
1 |
| 15 |
32439949 | High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression. | 2020 May 21 |
1 |
| 16 |
32694555 | The histone lysine methyltransferase SETD8 regulates angiogenesis through HES-1 in human umbilical vein endothelial cells. | 2020 Jul 21 |
1 |
| 17 |
32850975 | Inhibition of the SET8 Pathway Ameliorates Lung Fibrosis Even Through Fibroblast Dedifferentiation. | 2020 |
1 |
| 18 |
33028948 | SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN. | 2020 Oct |
1 |
| 19 |
33042742 | SETD8C302R Mutation Revealed from Myofibroblastoma-Discordant Monozygotic Twins Leads to p53/p21 Deficit and WEE1 Inhibitor Sensitivity. | 2020 Oct |
1 |
| 20 |
33127342 | SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma. | 2020 Dec |
2 |
| 21 |
33299050 | Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases. | 2020 Dec 9 |
2 |
| 22 |
31400111 | SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1. | 2019 Sep 26 |
1 |
| 23 |
31533987 | The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21. | 2019 Nov 1 |
2 |
| 24 |
30209253 | Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing. | 2018 Sep 12 |
1 |
| 25 |
28089831 | Monomethyltransferase SETD8 regulates breast cancer metabolism via stabilizing hypoxia-inducible factor 1α. | 2017 Apr 1 |
1 |
| 26 |
28249161 | The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling. | 2017 Feb 28 |
1 |
| 27 |
29186677 | The Methyltransferase Setd8 Is Essential for Erythroblast Survival and Maturation. | 2017 Nov 28 |
1 |
| 28 |
29250163 | miR-502-mediated histone methyltransferase SET8 expression is associated with clear cell renal cell carcinoma risk. | 2017 Dec |
1 |
| 29 |
27369108 | The Use of Nucleosome Substrates Improves Binding of SAM Analogs to SETD8. | 2016 Sep |
1 |
| 30 |
27411844 | Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors. | 2016 Aug 19 |
4 |
| 31 |
27688818 | The emerging role of lysine methyltransferase SETD8 in human diseases. | 2016 |
4 |
| 32 |
27940912 | Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. | 2016 Dec 27 |
1 |
| 33 |
24423864 | The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail 'histone code' and Riz1 tumor suppressor function. | 2014 Apr |
1 |
| 34 |
24459145 | A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. | 2014 Mar 14 |
2 |
| 35 |
24806961 | DNA polymerase α interacts with PrSet7 and mediates H4K20 monomethylation in Drosophila. | 2014 Jul 15 |
2 |
| 36 |
25032507 | Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. | 2014 Aug 14 |
1 |
| 37 |
25137013 | Small-molecule inhibitors of SETD8 with cellular activity. | 2014 Nov 21 |
4 |
| 38 |
25554733 | Structure-activity relationship studies of SETD8 inhibitors. | 2014 Dec |
4 |
| 39 |
23575530 | [The biological functions of lysine methyltransferase PR-SET7]. | 2013 Mar |
3 |
| 40 |
23720754 | microRNA-7 suppresses the invasive potential of breast cancer cells and sensitizes cells to DNA damages by targeting histone methyltransferase SET8. | 2013 Jul 5 |
2 |
| 41 |
22117221 | The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. | 2012 Feb 1 |
4 |
| 42 |
22556262 | Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. | 2012 Jul 1 |
2 |
| 43 |
22583696 | The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues. | 2012 Nov |
3 |
| 44 |
21200139 | A new regulator of the cell cycle: the PR-Set7 histone methyltransferase. | 2011 Jan 1 |
3 |
| 45 |
21282610 | Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. | 2011 Feb 22 |
1 |
| 46 |
21632252 | Coupling mitosis to DNA replication: the emerging role of the histone H4-lysine 20 methyltransferase PR-Set7. | 2011 Aug |
2 |
| 47 |
21829513 | The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression. | 2011 |
3 |
| 48 |
20512922 | PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression. | 2010 Jun 1 |
1 |
| 49 |
20932471 | CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation. | 2010 Oct 8 |
2 |
| 50 |
20932472 | CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. | 2010 Oct 8 |
1 |