| 1 |
35188729 | The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for Immunotherapy. | 2022 Mar 18 |
2 |
| 2 |
33732413 | Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1. | 2021 Mar 11 |
2 |
| 3 |
33859804 | Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. | 2021 Apr 8 |
2 |
| 4 |
33956554 | Inhibitors of immuno-oncology target HPK1 - a patent review (2016 to 2020). | 2021 Oct |
1 |
| 5 |
34166980 | MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway. | 2021 Jul |
1 |
| 6 |
34608799 | Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. | 2021 Oct 19 |
2 |
| 7 |
34908452 | The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε. | 2021 Dec 22 |
1 |
| 8 |
22902619 | Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein. | 2012 Oct 5 |
3 |
| 9 |
22105350 | Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation. | 2011 Nov 28 |
1 |
| 10 |
17353368 | A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. | 2007 Mar 19 |
3 |
| 11 |
15743830 | Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1. | 2005 Mar |
1 |
| 12 |
9891069 | Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase. | 1999 Feb |
1 |