Oligonucleotides

cyclin dependent kinase inhibitor 1A ; Homo sapiens







43 Article(s)
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1 23665321 Arginase inhibition reduces interleukin-1β-stimulated vascular smooth muscle cell proliferation by increasing nitric oxide synthase-dependent nitric oxide production. 2013 Jun 7 1
2 21776822 Evaluation of an 18F-labeled oligonucleotide probe targeting p21(WAF1) transcriptional changes in human tumor cells. 2011 2
3 18941111 MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. 2009 Jan 8 2
4 17486587 Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. 2008 Jan 1 2
5 18509005 Peroxisome proliferator-activated receptor gamma inhibits follicular and anaplastic thyroid carcinoma cells growth by upregulating p21Cip1/WAF1 gene in a Sp1-dependent manner. 2008 Jun 4
6 17408467 Iron deprivation blocks multilineage haematopoietic differentiation by inhibiting induction of p21(WAF1/CIP1). 2007 May 4
7 16376453 COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals. 2006 Mar 2
8 16904205 Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate. 2006 Sep 4
9 16970927 Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein. 2006 Dec 15 1
10 15705882 Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells. 2005 Feb 1 1
11 15767448 Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation. 2005 Apr 1
12 15920103 Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei. 2005 May 26 3
13 14761977 MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53. 2004 Apr 16 1
14 15294077 Downregulation of p21(WAF1/CIP1) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA). 2004 3
15 15466360 The calcium channel blocker amlodipine exerts its anti-proliferative action via p21(Waf1/Cip1) gene activation. 2004 Oct 3
16 12646420 Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth. 2003 Jul 1
17 12805427 p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax. 2003 Jul 2
18 11953864 Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21. 2002 Apr 8 1
19 12028050 Differentiation of functional dendritic cells and macrophages from human peripheral blood monocyte precursors is dependent on expression of p21 (WAF1/CIP1) and requires iron. 2002 Jun 1
20 11241357 A new molecular role for iron in regulation of cell cycling and differentiation of HL-60 human leukemia cells: iron is required for transcription of p21(WAF1/CIP1) in cells induced by phorbol myristate acetate. 2001 Apr 3
21 11386407 Overcoming of radioresistance in human gliomas by p21WAF1/CIP1 antisense oligonucleotide. 2001 Jan 3
22 11447172 Porphyromonas gingivalis fimbriae inhibit caspase-3-mediated apoptosis of monocytic THP-1 cells under growth factor deprivation via extracellular signal-regulated kinase-dependent expression of p21 Cip/WAF1. 2001 Aug 1
23 11521188 Identification of p21 as a target of cycloheximide-mediated facilitation of CD95-mediated apoptosis in human malignant glioma cells. 2001 Aug 9 1
24 11581254 A low abundance pool of nascent p21WAF1/Cip1 is targeted by estrogen to activate cyclin E*Cdk2. 2001 Nov 30 2
25 11767002 Role of transforming growth factor beta in the growth inhibition of human breast cancer cells by basic fibroblast growth factor. 2001 Nov 3
26 10617580 Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6). 2000 Jan 7 1
27 10692435 DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1). 2000 Mar 3 1
28 10698511 Anti-sense oligonucleotide of p21(waf1/cip1) prevents interleukin 4-mediated elevation of p27(kip1) in low grade astrocytoma cells. 2000 Feb 3 1
29 10698521 Interleukin-2 expression in human carcinoma cell lines and its role in cell cycle progression. 2000 Jan 27 2
30 10749849 The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. 2000 Jun 16 6
31 10769144 CRE-transcription factor decoy oligonucleotide inhibition of MCF-7 breast cancer cells: cross-talk with p53 signaling pathway. 2000 Apr 25 1
32 10991938 A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence. 2000 Dec 8 5
33 11055588 A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells. 2000 Aug 1
34 11072252 A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer. 2000 Dec 1 2
35 11199330 Elevated p21 mRNA level in skeletal muscle of DMD patients and mdx mice indicates either an exhausted satellite cell pool or a higher p21 expression in dystrophin-deficient cells per se. 2000 1
36 9889049 Antisense blockade of p21/WAF1 decreases radiation-induced G2 arrest in esophageal squamous cell carcinoma. 1999 Jan 2
37 10094816 Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. 1999 Apr 10 2
38 10517675 Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest. 1999 Oct 3
39 9440692 Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. 1998 Jan 15 1
40 9488044 Antisense oligonucleotide of WAF1 gene prevents EGF-induced cell-cycle arrest in A431 cells. 1998 Feb 12 1
41 9694869 Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells. 1998 Aug 14 1
42 9736735 Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins. 1998 Sep 15 1
43 7743505 Radiation-induced G1 arrest is selectively mediated by the p53-WAF1/Cip1 pathway in human thyroid cells. 1995 May 15 4