Vorinostat

cyclin dependent kinase inhibitor 1A ; Homo sapiens







42 Article(s)
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1 32335549 MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells. 2021 1
2 34066975 Effect of the HDAC Inhibitor on Histone Acetylation and Methyltransferases in A2780 Ovarian Cancer Cells. 2021 May 7 2
3 32878786 CDKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality. 2020 Sep 1
4 30307360 The histone deacetylase inhibitor Suberoylanilide Hydroxamic Acid (SAHA) as a therapeutic agent in rhabdomyosarcoma. 2019 2
5 27926517 Suberoylanilide hydroxamic acid-induced specific epigenetic regulation controls Leptin-induced proliferation of breast cancer cell lines. 2017 Jan 10 2
6 28123594 Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells. 2017 2
7 27697993 Retraction: Synergistic Interactions between Vorinostat and Sorafenib in Chronic Myelogenous Leukemia Cells Involve Mcl-1 and p21CIP1 Down-Regulation. 2016 Oct 1 1
8 26178881 Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy. 2015 Jul 16 3
9 26506264 p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia. 2015 6
10 24639460 P21-driven multifusion gene system for evaluating the efficacy of histone deacetylase inhibitors by in vivo molecular imaging and for transcription targeting therapy of cancer mediated by histone deacetylase inhibitor. 2014 Apr 2
11 24686006 Superior activity of a new histone deacetylase inhibitor (ZYJ-34c) in inhibiting growth of human leukemia cells by inducing p21WAF1 expression and cell cycle arrest. 2014 Aug 1
12 24886166 Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells. 2014 May 27 1
13 23515411 A phase I trial of vorinostat and alvocidib in patients with relapsed, refractory, or poor prognosis acute leukemia, or refractory anemia with excess blasts-2. 2013 Apr 1 1
14 23536727 Expression of leukemia-associated fusion proteins increases sensitivity to histone deacetylase inhibitor-induced DNA damage and apoptosis. 2013 Aug 2
15 21598070 Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures. 2011 Nov 1
16 21903579 p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia. 2011 Oct 28 2
17 21931726 The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway. 2011 2
18 19875160 Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines. 2010 Jan 2
19 20202195 Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. 2010 Mar 4 2
20 20384633 Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression. 2010 Jun 1
21 20846458 Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells. 2010 Sep 17 1
22 19330811 Variations in c-Myc and p21WAF1 expression protect normal peripheral blood lymphocytes against BimEL-mediated cell death. 2009 Apr 4
23 18850582 SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway. 2008 Dec 4
24 17417771 Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. 2007 Aug 1 2
25 17499001 HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway. 2007 3
26 17634558 Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation. 2007 Jul 15 7
27 17638911 Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels. 2007 Jul 15 1
28 16015388 Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells. 2005 Sep 1
29 16144943 Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2. 2005 Sep 1 2
30 16297208 Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action. 2005 Nov 4
31 14734806 Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. 2004 Feb 3 6
32 12727828 Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and -resistant Bcr/Abl+ human myeloid leukemia cells. 2003 May 1 2
33 12893773 The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. 2003 Nov 15 1
34 14614324 Induction of apoptosis in BCR/ABL+ cells by histone deacetylase inhibitors involves reciprocal effects on the RAF/MEK/ERK and JNK pathways. 2003 Sep-Oct 1
35 14654560 Histone deacetylase inhibitors induce growth suppression and cell death in human rhabdomyosarcoma in vitro. 2003 Nov 15 2
36 14679005 Coadministration of the heat shock protein 90 antagonist 17-allylamino- 17-demethoxygeldanamycin with suberoylanilide hydroxamic acid or sodium butyrate synergistically induces apoptosis in human leukemia cells. 2003 Dec 1 3
37 11831887 Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. 2002 Feb 14 3
38 12094258 Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). 2002 Jul 2
39 10954755 Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. 2000 Aug 29 6
40 11126200 Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment. 2000 Oct 1
41 11126357 Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites. 2000 Nov 23 7
42 10597302 Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53. 1999 Nov 25 4