Tretinoin

cyclin dependent kinase inhibitor 1A ; Homo sapiens







48 Article(s)
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1 31485618 Clofarabine‑phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase‑dependent apoptosis. 2019 Oct 2
2 24821728 Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genes. 2014 Jul 4 2
3 25072246 A PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation. 2014 1
4 21437295 Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells. 2011 May 1
5 20403807 Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes. 2010 Aug 2
6 20428830 The cleavage fragment of retinoid X receptor-alpha ligand binding domain inhibits radiosensitization by retinoic acid. 2010 Jun 1
7 20564173 Synergic effect of retinoic acid and extremely low frequency magnetic field exposure on human neuroblastoma cell line BE(2)C. 2010 Sep 3
8 19633294 Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells. 2009 Sep 25 5
9 20193324 [Differentiating effect of PPARgamma ligand rosiglitazone and all trans-retinoic acid on myeloma cells and its possible mechanism]. 2009 Dec 2
10 18006504 A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. 2008 Feb 15 3
11 18280804 Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids. 2008 Apr 18 3
12 18773862 Retinoic acid and sodium butyrate as cell cycle regulators in the treatment of oral squamous carcinoma cells. 2008 2
13 19035179 [Growth inhibition of human leukemia cell line U937 by all-trans retinoic acid and its mechanism]. 2008 Jul 1
14 17656367 p21WAF1/CIP1 is a common transcriptional target of retinoid receptors: pleiotropic regulatory mechanism through retinoic acid receptor (RAR)/retinoid X receptor (RXR) heterodimer and RXR/RXR homodimer. 2007 Oct 12 2
15 16223781 Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells. 2006 Feb 15 1
16 17166369 [Synergistic inhibitory effect of all-trans retinoic acid and 1,25-dihydroxy vitamin D3 on growth of human hepatoma cell line HepG2]. 2006 Dec 2
17 15645120 Promotion of cell differentiation, and suppression of cell growth and cyclooxygenase-2 expression by differentiation-inducing agents in human oral squamous carcinoma SCC25 cells. 2005 Feb 1
18 15949692 Retinoic acid modulates the retinoblastoma protein during adipocyte terminal differentiation. 2005 May 30 2
19 15024057 Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. 2004 Apr 6
20 15256728 Implication of CDK inhibitors p21 and p27 in the differentiation of HL-60 cells. 2004 Jul 2
21 12516107 Ectopic p21sdi1 gene transfer induces retinoic acid receptor beta expression and sensitizes human cancer cells to retinoid treatment. 2003 Mar 1 2
22 12955881 Retinoic acid modulates the cell-cycle in fetal rat hepatocytes and HepG2 cells by regulating cyclin-cdk activities. 2003 Jun 1
23 13679204 Establishment and characterization of a cell line from smokeless tobacco associated oral squamous cell carcinoma. 2003 Dec 3
24 11877298 Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1). 2002 Mar 15 3
25 11886382 Interleukin 10 abolishes the growth inhibitory effects of all-trans retinoic acid on human myeloma cells. 2002 Mar 4
26 12012012 All trans retinoic acid enhances CDDP-induced apoptosis: modulation of the CDDP effect on cell cycle progression. 2002 Jun 1
27 12404122 Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation. 2002 Nov 1
28 11519864 1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects. 2001 May 1
29 11694457 Retinoic acid protects against hyperoxia-mediated cell-cycle arrest of lung alveolar epithelial cells by preserving late G1 cyclin activities. 2001 Oct 4
30 11780391 Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression. 2001 Sep 1
31 10645889 Retinoic acid-induced proliferation of lung alveolar epithelial cells is linked to p21(CIP1) downregulation. 2000 Jan 6
32 10816444 Bcl-2 accelerates retinoic acid-induced growth arrest and recovery in human gastric cancer cells. 2000 Jun 1 4
33 10896783 Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells. 2000 Aug 1 3
34 10090931 1,25-Dihydroxyvitamin D3 induces differentiation of a retinoic acid-resistant acute promyelocytic leukemia cell line (UF-1) associated with expression of p21(WAF1/CIP1) and p27(KIP1). 1999 Apr 1 2
35 10094816 Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. 1999 Apr 10 8
36 10356361 Transcriptional activation of the cyclin-dependent kinase inhibitor p21 by PML/RARalpha. 1999 May 2
37 10359529 A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest. 1999 May 27 2
38 10381520 Growth inhibition of a human myeloma cell line by all-trans retinoic acid is not mediated through downregulation of interleukin-6 receptors but through upregulation of p21(WAF1). 1999 Jul 1 6
39 10438723 Retinoic acid prevents phosphorylation of pRB in normal human B lymphocytes: regulation of cyclin E, cyclin A, and p21(Cip1). 1999 Aug 15 6
40 12548778 [Regulation of cell cycle by retinoic acid in gastric cancer cells]. 1999 Jun 1
41 9607768 Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. 1998 May 21 1
42 9716179 Increased cdc2 and cdk2 kinase activity by retinoid X receptor gamma-mediated transcriptional down-regulation of the cyclin-dependent kinase inhibitor p21Cip1/WAF1 correlates with terminal differentiation of squamous cell carcinoma lines. 1998 Aug 2
43 9889406 Apoptosis and growth inhibition of squamous carcinoma cells treated with interferon-alpha, IFN-beta and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21. 1998 Dec 1
44 9929163 Apoptosis is induced in aging SV40 T antigen-transformed human fibroblasts through p53- and p21CIP1/WAF1-independent pathways. 1998 Nov 13 1
45 9225073 Modulation of p53, WAF1/p21 and BCL-2 expression during retinoic acid-induced differentiation of NB4 promyelocytic cells. 1997 May 2
46 8760353 Reversal of the temperature-shift-induced growth restriction of a temperature-sensitive simian virus 40 T-antigen-transformed human fibroblast cell line by treatment with retinoic acid. 1996 Aug 1 6
47 8940196 Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. 1996 Dec 6 3
48 7936668 Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. 1994 Nov 1