| 1 |
35184673 | Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment. | 2022 Mar |
1 |
| 2 |
33966040 | Inhibition of the sonic hedgehog pathway activates TGF-β-activated kinase (TAK1) to induce autophagy and suppress apoptosis in thyroid tumor cells. | 2021 May 8 |
1 |
| 3 |
34504485 | Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. | 2021 |
1 |
| 4 |
34676048 | TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan. | 2021 Oct 12 |
1 |
| 5 |
31376257 | IL-17A upregulates P-glycoprotein expression in peripheral blood lymphocytes of patients with rheumatoid arthritis through TAK1. | 2020 Mar-Apr |
1 |
| 6 |
32108376 | TAK1 signaling activity links the mast cell cytokine response and degranulation in allergic inflammation. | 2020 Apr |
4 |
| 7 |
33086897 | Synthesis and biological activity of 2-cyanoacrylamide derivatives tethered to imidazopyridine as TAK1 inhibitors. | 2020 Dec |
1 |
| 8 |
30850732 | TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma. | 2019 Dec |
5 |
| 9 |
31539775 | Role of TGF-β-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. | 2019 Nov |
1 |
| 10 |
29027124 | TAK1 inhibition ameliorates survival from graft-versus-host disease in an allogeneic murine marrow transplantation model. | 2018 Feb |
1 |
| 11 |
29373048 | Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose. | 2018 Apr |
1 |
| 12 |
29777109 | TAK1 mediates microenvironment-triggered autocrine signals and promotes triple-negative breast cancer lung metastasis. | 2018 May 18 |
2 |
| 13 |
27820799 | Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation. | 2017 Jan |
4 |
| 14 |
27876620 | The GABAB positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABAB receptors. | 2017 Jan 5 |
2 |
| 15 |
28039587 | TGF-β Down-regulates Apolipoprotein M Expression through the TAK-1-JNK-c-Jun Pathway in HepG2 Cells. | 2017 Feb |
2 |
| 16 |
28111999 | Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in Molt-4 cells. | 2017 Jun |
3 |
| 17 |
28224764 | Transforming growth factor β-activated kinase 1 inhibitor suppresses the proliferation in triple-negative breast cancer through TGF-β/TGFR pathway. | 2017 Sep |
2 |
| 18 |
28389629 | Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation. | 2017 May 2 |
1 |
| 19 |
28430599 | TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis. | 2017 May 16 |
2 |
| 20 |
28668088 | Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-α stimulation of synovial cells: an in vitro study. | 2017 Jul 1 |
1 |
| 21 |
28714004 | Expression and function of transforming growth factor‑β‑activated protein kinase 1 in gastric cancer. | 2017 Sep |
3 |
| 22 |
26227222 | Synergistic action of 5Z-7-oxozeaenol and bortezomib in inducing apoptosis of Burkitt lymphoma cell line Daudi. | 2016 Jan |
4 |
| 23 |
26687627 | Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages. | 2016 Feb |
2 |
| 24 |
27448221 | Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cells. | 2016 Sep |
2 |
| 25 |
25557171 | Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer. | 2015 Jan 20 |
4 |
| 26 |
25927238 | 5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts. | 2015 |
2 |
| 27 |
26100626 | TGFβ-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage. | 2015 Aug 7 |
5 |
| 28 |
26114584 | Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells. | 2015 Aug |
2 |
| 29 |
26291056 | TAK1-regulated expression of BIRC3 predicts resistance to preoperative chemoradiotherapy in oesophageal adenocarcinoma patients. | 2015 Sep 15 |
1 |
| 30 |
26481152 | Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues. | 2015 Nov 1 |
2 |
| 31 |
26491199 | Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses. | 2015 Dec 1 |
1 |
| 32 |
26823762 | The role of TAK1 expression in thyroid cancer. | 2015 |
1 |
| 33 |
24874739 | Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef. | 2014 May 29 |
1 |
| 34 |
25118260 | TAK1 inhibition accelerates cellular senescence of retinal pigment epithelial cells. | 2014 Aug 12 |
1 |
| 35 |
25277189 | Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling. | 2014 Sep 15 |
2 |
| 36 |
23022457 | TAK1 inhibition for treatment of cerebral ischemia. | 2013 Jan |
1 |
| 37 |
23272696 | Mechanism and in vitro pharmacology of TAK1 inhibition by (5Z)-7-Oxozeaenol. | 2013 Mar 15 |
9 |
| 38 |
23700229 | TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy. | 2013 Oct |
2 |
| 39 |
22523282 | Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells. | 2012 Aug 1 |
1 |
| 40 |
22628200 | BMP2 induces osteoblast apoptosis in a maturation state and noggin-dependent manner. | 2012 Oct |
1 |
| 41 |
21873447 | TAK1 plays a major role in growth factor-induced phenotypic modulation of airway smooth muscle. | 2011 Nov |
1 |
| 42 |
22171160 | NF-κB feedback control of JNK1 activation modulates TRPV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells. | 2011 |
2 |
| 43 |
20200282 | Constitutive association of TGF-beta-activated kinase 1 with the IkappaB kinase complex in the nucleus and cytoplasm of human neutrophils and its impact on downstream processes. | 2010 Apr 1 |
1 |
| 44 |
17348859 | Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. | 2007 Jun 1 |
5 |
| 45 |
17172402 | Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade. | 2006 Dec |
1 |
| 46 |
12624112 | A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase. | 2003 May 16 |
5 |