1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one

phosphodiesterase 10A ; Homo sapiens







6 Article(s)
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Title
Pub. Year
#Total Relationships
1 32598478 Translational Development Strategies for TAK-063, a Phosphodiesterase 10A Inhibitor. 2020 Nov 26 1
2 29318783 TAK-063, a novel PDE10A inhibitor with balanced activation of direct and indirect pathways, provides a unique opportunity for the treatment of schizophrenia. 2018 Jul 2
3 28381659 A strategy to improve the success rate of CNS drug development: TAK-063, a novel PDE10A inhibitor, as a case study. 2017 1
4 29103081 A Randomized Multiple Dose Pharmacokinetic Study of a Novel PDE10A Inhibitor TAK-063 in Subjects with Stable Schizophrenia and Japanese Subjects and Modeling of Exposure Relationships to Adverse Events. 2017 Dec 2
5 27423256 A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor. 2016 Nov 1 5
6 27572830 A phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAK-063, a selective PDE10A inhibitor. 2016 Oct 1