| 1 |
34044147 | Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease. | 2021 Aug |
1 |
| 2 |
31951013 | Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease. | 2020 Aug |
1 |
| 3 |
32610340 | Activation of tyrosine phosphatase PTP1B in pyramidal neurons impairs endocannabinoid signaling by tyrosine receptor kinase trkB and causes schizophrenia-like behaviors in mice. | 2020 Oct |
1 |
| 4 |
29059712 | Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor. | 2018 Jan |
1 |
| 5 |
26328540 | Combination of PKCε Activation and PTP1B Inhibition Effectively Suppresses Aβ-Induced GSK-3β Activation and Tau Phosphorylation. | 2016 Sep |
1 |
| 6 |
27251941 | The phosphatidylethanolamine derivative diDCP-LA-PE mimics intracellular insulin signaling. | 2016 Jun 2 |
1 |
| 7 |
26214522 | PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. | 2015 Aug 3 |
2 |
| 8 |
24668740 | Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-Ay mice. | 2014 Jun |
1 |
| 9 |
23521888 | Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina. | 2013 Mar 22 |
4 |
| 10 |
23571270 | CB₁ cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells. | 2013 Aug |
1 |
| 11 |
23590304 | The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction. | 2013 Nov |
1 |
| 12 |
23661004 | Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. | 2013 May 9 |
1 |
| 13 |
23702782 | Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice. | 2013 Jun 19 |
2 |
| 14 |
23711960 | Protein tyrosine phosphatase 1B inhibits adipocyte differentiation and mediates TNFα action in obesity. | 2013 Aug |
3 |
| 15 |
22458296 | Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading. | 2012 Jun |
1 |
| 16 |
22807119 | Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid. | 2012 Dec |
2 |
| 17 |
22844492 | Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning. | 2012 |
2 |
| 18 |
23085227 | Pyrroloquinoline quinone, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves impaired glucose tolerance in diabetic KK-A(y) mice. | 2012 Nov 16 |
2 |
| 19 |
20506299 | PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I. | 2010 Oct |
1 |
| 20 |
18515860 | Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics. | 2008 Sep |
1 |
| 21 |
17068137 | Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes. | 2007 Feb |
1 |
| 22 |
17259385 | Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance. | 2007 Feb |
1 |
| 23 |
17545163 | Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. | 2007 Aug 17 |
1 |
| 24 |
17576811 | Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets. | 2007 Sep |
1 |
| 25 |
16363874 | In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach. | 2006 Feb |
2 |
| 26 |
15699041 | Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice. | 2005 Apr 15 |
1 |
| 27 |
16115959 | PTP-1B is an essential positive regulator of platelet integrin signaling. | 2005 Aug 29 |
2 |
| 28 |
14693698 | Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice. | 2004 Jan |
1 |
| 29 |
14766979 | The role of protein tyrosine phosphatase 1B in Ras signaling. | 2004 Feb 17 |
2 |
| 30 |
14966296 | Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase. | 2004 Mar |
1 |
| 31 |
15226396 | Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer. | 2004 Jul 1 |
3 |
| 32 |
12748279 | Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling. | 2003 Jun |
2 |
| 33 |
12354677 | Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line. | 2002 Sep 30 |
1 |
| 34 |
11346638 | Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B. | 2001 Jul 13 |
1 |
| 35 |
11694501 | TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B. | 2001 Dec 21 |
1 |
| 36 |
12477292 | Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance. | 2001 Nov |
1 |
| 37 |
9813103 | Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. | 1998 Nov 2 |
2 |
| 38 |
8622647 | Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation. | 1996 Mar |
1 |