Cholesterol

translocator protein ; Homo sapiens







134 Article(s)
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1 35352645 Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging. 2022 Mar 29 2
2 35444539 Comparative Assessment of TSPO Modulators on Electroencephalogram Activity and Exploratory Behavior. 2022 1
3 35522669 Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant. 2022 2
4 31713961 TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity. 2021 Jan 6
5 32881658 The Ligands of Translocator Protein: Design and Biological Properties. 2021 1
6 33354729 Membrane-embedded TSPO: an NMR view. 2021 Mar 2
7 33652554 The Interplay of Cholesterol and Ligand Binding in hTSPO from Classical Molecular Dynamics Simulations. 2021 Feb 26 2
8 33769215 Variation rs6971 in the Translocator Protein Gene (TSPO) is Associated with Aggressiveness and Impulsivity but Not with Anxiety in a Population-Representative Sample of Young Adults. 2021 Mar-May 3
9 33965043 Cholesterol was identified as a biomarker in human melanocytic nevi using DESI and DESI/PI mass spectrometry imaging. 2021 Aug 15 2
10 34013171 Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease. 2021 May 21 4
11 31536662 Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies. 2020 Jan 2
12 32065102 A Protective Role of Translocator Protein in Alzheimer's Disease Brain. 2020 2
13 32387458 18-kDa translocator protein association complexes in the brain: From structure to function. 2020 Jul 1
14 32697916 Versatile Dimerisation Process of Translocator Protein (TSPO) Revealed by an Extensive Sampling Based on a Coarse-Grained Dynamics Study. 2020 Aug 24 1
15 30457052 Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands. 2019 3
16 30699908 Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism. 2019 Jan 29 1
17 30714368 BDE-47 Decreases Progesterone Levels in BeWo Cells by Interfering with Mitochondrial Functions and Genes Related to Cholesterol Transport. 2019 Apr 15 1
18 30893912 Deletion of TSPO Resulted in Change of Metabolomic Profile in Retinal Pigment Epithelial Cells. 2019 Mar 19 1
19 31288390 VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States. 2019 Jul 8 2
20 31323920 CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells. 2019 Jul 9 1
21 28667781 Translocator protein (18 kDa): an update on its function in steroidogenesis. 2018 Feb 2
22 28875261 The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site. 2018 Mar 1
23 29315754 TSPO regulation in reactive gliotic diseases. 2018 Jun 1
24 29641545 Effects of genetic variants in the TSPO gene on protein structure and stability. 2018 1
25 29777199 Influence of alcoholism and cholesterol on TSPO binding in brain: PET [11C]PBR28 studies in humans and rodents. 2018 Aug 4
26 30255522 Insights into Cholesterol/Membrane Protein Interactions Using Paramagnetic Solid-State NMR. 2018 Nov 27 3
27 30308949 Induction of ATP Release, PPIX Transport, and Cholesterol Uptake by Human Red Blood Cells Using a New Family of TSPO Ligands. 2018 Oct 10 1
28 30477223 TSPO Ligands Promote Cholesterol Efflux and Suppress Oxidative Stress and Inflammation in Choroidal Endothelial Cells. 2018 Nov 24 8
29 27990801 Tryptophan-Rich Sensory Protein/Translocator Protein (TSPO) from Cyanobacterium Fremyella diplosiphon Binds a Broad Range of Functionally Relevant Tetrapyrroles. 2017 Jan 10 2
30 28156095 Optimized Translocator Protein Ligand for Optical Molecular Imaging and Screening. 2017 Apr 19 1
31 28235666 Identification of novel anti cancer agents by applying insilico methods for inhibition of TSPO protein. 2017 Jun 1
32 28240002 Cholesterol Homeostasis in Isolated Lymphocytes: a Differential Correlation Between Male Control and Chronic Lymphocytic Leukemia Subjects 2017 Jan 1 1
33 28358007 Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure. 2017 Mar 30 4
34 28442392 4'-Chlorodiazepam is neuroprotective against amyloid-beta in organotypic hippocampal cultures. 2017 Jul 2
35 28973423 Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration. 2017 Nov 15 7
36 29054730 The translocator protein (18kDa) and its role in neuropsychiatric disorders. 2017 Dec 1
37 29074640 TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis. 2017 Nov 21 2
38 29299119 Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches. 2017 Dec 15 1
39 29318061 Adrenal Oncocytic Neoplasm with Paradoxical Loss of Important Mitochondrial Steroidogenic Protein: The 18 kDA Translocator Protein. 2017 1
40 26589093 Neurosteroids in hepatic encephalopathy: Novel insights and new therapeutic opportunities. 2016 Jun 1
41 26688086 Mitochondrial translocator protein (TSPO): From physiology to cardioprotection. 2016 Apr 1 2
42 26707976 4'-Chlorodiazepam is neuroprotective against amyloid-beta through the modulation of survivin and bax protein expression in vitro. 2016 Feb 1 2
43 26741196 Translocator Protein (TSPO) Affects Mitochondrial Fatty Acid Oxidation in Steroidogenic Cells. 2016 Mar 1
44 26750656 TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy. 2016 Jan 11 2
45 27039042 Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis. 2016 Sep 1
46 27382207 Differential Expressions of p53, p53R2, hRRM2 and PBR in Chronic Lymphocytic Leukemia: A Correlation with Intracellular Cholesterol. 2016 Jul 2
47 27599163 Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010 - 2015; part 2). 2016 Nov 1
48 27608010 Regulation of Translocator Protein 18 kDa (TSPO) Expression in Rat and Human Male Germ Cells. 2016 Sep 6 4
49 25322273 Obesity-induced down-regulation of the mitochondrial translocator protein (TSPO) impairs placental steroid production. 2015 Jan 2
50 25635101 Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. 2015 Jan 30 3