sirtinol

sirtuin 2 ; Homo sapiens







12 Article(s)
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1 30067423 Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer. 2018 2
2 28127057 Sirtinol promotes PEPCK1 degradation and inhibits gluconeogenesis by inhibiting deacetylase SIRT2. 2017 Feb 28 3
3 25829495 Sirtuin Inhibition Induces Apoptosis-like Changes in Platelets and Thrombocytopenia. 2015 May 8 1
4 25924011 Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation. 2015 1
5 23382805 Identification of inhibitor binding site in human sirtuin 2 using molecular docking and dynamics simulations. 2013 1
6 23499872 The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock. 2013 Jun 1
7 22564257 Molecular docking and dynamics simulation, receptor-based hypothesis: application to identify novel sirtuin 2 inhibitors. 2012 Aug 1
8 22694102 Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding. 2012 1
9 20371709 SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. 2010 Apr 2
10 17181175 N,N'-Bisbenzylidenebenzene-1,4-diamines and N,N'-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors. 2006 Dec 28 1
11 15860278 Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase. 2005 May 1
12 15486319 Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. 2004 Nov 12 1