44 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35358824 | Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity. | 2022 Jun | 2 |
2 | 35441145 | Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration. | 2022 Apr 6 | 1 |
3 | 33316537 | SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma. | 2021 Jan | 2 |
4 | 33546767 | NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells. | 2021 Feb 5 | 1 |
5 | 33789098 | SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. | 2021 Mar 30 | 1 |
6 | 34429771 | Emerging role of SIRT2 in non-small cell lung cancer. | 2021 Oct | 1 |
7 | 34458803 | Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration. | 2021 Apr 1 | 2 |
8 | 34601098 | Acetylation of ANXA1 reduces caspase-3 activation by enhancing the phosphorylation of caspase-9 under OGD/R conditions. | 2021 Dec | 1 |
9 | 34618427 | Genetically Encoded Benzoyllysines Serve as Versatile Probes for Interrogating Histone Benzoylation and Interactions in Living Cells. | 2021 Nov 19 | 2 |
10 | 34961760 | Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2. | 2021 Dec 28 | 1 |
11 | 32112098 | Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer. | 2020 Apr 17 | 1 |
12 | 32941003 | Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene. | 2020 Oct 13 | 2 |
13 | 33214845 | Simultaneous Inhibition of SIRT2 Deacetylase and Defatty-Acylase Activities via a PROTAC Strategy. | 2020 Nov 12 | 1 |
14 | 30734528 | A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation. | 2019 Apr 3 | 2 |
15 | 31366618 | LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. | 2019 Oct 3 | 2 |
16 | 31433161 | SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration. | 2019 Sep 20 | 1 |
17 | 31644285 | Chemical Probes Reveal Sirt2's New Function as a Robust "Eraser" of Lysine Lipoylation. | 2019 Nov 20 | 3 |
18 | 30154464 | Lysine benzoylation is a histone mark regulated by SIRT2. | 2018 Aug 28 | 1 |
19 | 30213795 | SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. | 2018 Nov | 1 |
20 | 29239724 | SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a. | 2017 Dec 14 | 1 |
21 | 26854234 | ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. | 2016 Feb 16 | 1 |
22 | 27311481 | SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. | 2016 Aug 1 | 1 |
23 | 27586085 | SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation. | 2016 Sep 2 | 1 |
24 | 27783945 | The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer. | 2016 Oct 25 | 1 |
25 | 25476551 | Integrative chemical biology approaches for identification and characterization of "erasers" for fatty-acid-acylated lysine residues within proteins. | 2015 Jan 19 | 1 |
26 | 25195573 | Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity. | 2014 Oct | 1 |
27 | 25285631 | Deacetylation of the mitotic checkpoint protein BubR1 at lysine 250 by SIRT2 and subsequent effects on BubR1 degradation during the prometaphase/anaphase transition. | 2014 Oct 24 | 1 |
28 | 25369635 | Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach. | 2014 Nov 4 | 1 |
29 | 25384215 | NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells. | 2014 Dec | 1 |
30 | 23175188 | The histone deacetylase SIRT2 stabilizes Myc oncoproteins. | 2013 Mar | 1 |
31 | 23358244 | Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. | 2013 Feb 4 | 2 |
32 | 22694102 | Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding. | 2012 | 1 |
33 | 19914676 | Substrate specificity of SIRT1-catalyzed lysine Nepsilon-deacetylation reaction probed with the side chain modified Nepsilon-acetyl-lysine analogs. | 2010 Feb | 1 |
34 | 20630764 | N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2. | 2010 Aug 1 | 2 |
35 | 19413317 | Inhibition of human sirtuins by in situ generation of an acetylated lysine-ADP-ribose conjugate. | 2009 May 27 | 1 |
36 | 18995842 | The SIRT2 deacetylase regulates autoacetylation of p300. | 2008 Nov 7 | 1 |
37 | 17456799 | Sirtuin functions in health and disease. | 2007 Aug | 2 |
38 | 17694090 | NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. | 2007 Aug 13 | 1 |
39 | 17951578 | Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases. | 2007 Dec 21 | 2 |
40 | 18027980 | Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide. | 2007 Dec 18 | 2 |
41 | 16648462 | SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. | 2006 May 15 | 1 |
42 | 16076959 | Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. | 2005 Aug 9 | 3 |
43 | 12620231 | The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. | 2003 Feb | 1 |
44 | 14522996 | Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. | 2003 Dec 19 | 2 |