beta-Lactams

solute carrier family 15 member 1 ; Homo sapiens







26 Article(s)
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1 33015026 Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism - Update to the Human Model and Expansion of Applications. 2020 1
2 20370696 Bioavailability through PepT1: the role of computer modelling in intelligent drug design. 2010 Mar 1
3 18957377 Review. The mammalian proton-coupled peptide cotransporter PepT1: sitting on the transporter-channel fence? 2009 Jan 27 2
4 19371738 PEPT1 involved in the uptake and transepithelial transport of cefditoren in vivo and in vitro. 2009 Jun 10 1
5 19389486 The transmembrane tyrosines Y56, Y91 and Y167 play important roles in determining the affinity and transport rate of the rabbit proton-coupled peptide transporter PepT1. 2009 Nov 1
6 19519280 Transport of drugs by proton-coupled peptide transporters: pearls and pitfalls. 2009 Aug 1
7 19652390 Direct evidence for efficient transport and minimal metabolism of L-cephalexin by oligopeptide transporter 1 in budded baculovirus fraction. 2009 Aug 1
8 18037334 Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1. 2008 1
9 18353114 Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter. 2008 Apr 1
10 17142565 Functional expression of stereoselective metabolism of cephalexin by exogenous transfection of oligopeptide transporter PEPT1. 2007 Mar 1
11 15567297 Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. 2005 Jan 2
12 15974593 Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. 2005 Jun 30 1
13 12548404 Expression of the peptide transporter hPepT1 in human colon: a potential route for colonic protein nitrogen and drug absorption. 2003 Jan 1
14 12816347 Di/tri-peptide transporters as drug delivery targets: regulation of transport under physiological and patho-physiological conditions. 2003 Jul 1
15 14561585 Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. 2003 Nov 1
16 14567632 Inhibitory effect of zinc on PEPT1-mediated transport of glycylsarcosine and beta-lactam antibiotics in human intestinal cell line Caco-2. 2003 Sep 2
17 11808341 [Molecular mechanisms on drug transporters in the drug absorption and disposition]. 2002 Jan 1
18 11561098 Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells. 2001 Oct 1
19 10636865 beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. 2000 Jan 21 1
20 9950279 Intestinal transport of beta-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux. 1999 Jan 1
21 10052994 CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs. 1999 Mar 2
22 10362647 Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2. 1999 Jun 1
23 9126331 Expression and functional characterization of the mammalian intestinal peptide transporter PepT1 in the methylotropic yeast Pichia pastoris. 1997 Mar 27 2
24 9207295 The oligopeptide transporter (Pept-1) in human intestine: biology and function. 1997 Jul 1
25 8627565 Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells. 1996 May 2
26 7592745 Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. 1995 Oct 27 2