Dinoprostone

prostaglandin E receptor 2 (subtype EP2) ; Mus musculus







182 Article(s)
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1 34862858 Bone marrow mesenchymal stem cell-derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors. 2022 Feb 1
2 34938150 Changing prostaglandin E2 (PGE2) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE2 receptor EP2 and EP4. 2022 Jan 3
3 35260562 PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis. 2022 Mar 9 1
4 35543149 Reduced tumor growth in EP2 knockout mice is related to signaling pathways favoring an increased local anti‑tumor immunity in the tumor stroma. 2022 Jun 1
5 33035633 Inhibition of lysophosphatidic acid receptor 1 attenuates neuroinflammation via PGE2/EP2/NOX2 signalling and improves the outcome of intracerebral haemorrhage in mice. 2021 Jan 1
6 33465467 Multiple 'omics'-analysis reveals the role of prostaglandin E2 in Hirschsprung's disease. 2021 Feb 20 1
7 33473210 Restoring metabolism of myeloid cells reverses cognitive decline in ageing. 2021 Feb 1
8 33786738 The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD2 or PGE2. 2021 Jun 1
9 33848272 Hunger-promoting AgRP neurons trigger an astrocyte-mediated feed-forward autoactivation loop in mice. 2021 May 17 1
10 33850845 Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity. 2021 Mar 1
11 34031121 Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy. 2021 Oct 1
12 34405216 [Overexpression of human EP4 receptor in vascular smooth muscle cells attenuates angiotensin II-induced hypertension in mice]. 2021 Aug 25 1
13 34598950 Firefighters for the Wrong Type of Inflammation in Tumors. 2021 Oct 1
14 34712420 Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2. 2021 Jul 3
15 34974067 Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma. 2021 Dec 30 1
16 31490357 EP2 Receptor Blockade Attenuates COX-2 Upregulation During Intestinal Inflammation. 2020 Sep 1
17 31617678 Role of the PGE2 receptor subtypes EP1, EP2, and EP3 in repetitive traumatic brain injury. 2020 Jun 1
18 31715338 CYLD, a mechanosensitive deubiquitinase, regulates TGFβ signaling in load-induced bone formation. 2020 Feb 1
19 32407837 PGE2 deficiency predisposes to anaphylaxis by causing mast cell hyperresponsiveness. 2020 Dec 1
20 32411331 Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells. 2020 5
21 32432758 Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF-β1-induced renal fibrosis by regulating endoplasmic reticulum stress. 2020 May 1
22 32484881 Lung fibroblasts produce IL-33 in response to stimulation with retinoblastoma-binding protein 9 via production of prostaglandin E2. 2020 Sep 30 1
23 32502905 Manganese exposure caused reproductive toxicity of male mice involving activation of GnRH secretion in the hypothalamus by prostaglandin E2 receptors EP1 and EP2. 2020 Sep 15 4
24 32622526 The positive effect of selective prostaglandin E2 receptor EP2 and EP4 blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo. 2020 Aug 1
25 32820026 PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking. 2020 Nov 4
26 33059704 Cyclooxygenase-1 mediates neuroinflammation and neurotoxicity in a mouse model of retinitis pigmentosa. 2020 Oct 15 6
27 29935220 T cell-intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell-driven inflammation. 2019 Feb 2
28 30763657 Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury. 2019 May 1 3
29 30926983 Molecular mechanisms underlying prostaglandin E2-exacerbated inflammation and immune diseases. 2019 Aug 23 1
30 31036664 PGE2 signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia. 2019 May 14 5
31 31054202 Activation of the prostaglandin E2 EP2 receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices. 2019 Sep 1
32 31243090 Cyclooxygenase-1 Regulates the Development of Follicular Th Cells via Prostaglandin E2. 2019 Aug 15 1
33 31301371 Prostaglandin E2 (PGE2)-EP2 signaling negatively regulates murine atopic dermatitis-like skin inflammation by suppressing thymic stromal lymphopoietin expression. 2019 Nov 4
34 28589946 Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1β-related lung injury. 2018 Mar 2
35 28687401 Pathophysiological role of prostaglandin E2-induced up-regulation of the EP2 receptor in motor neuron-like NSC-34 cells and lumbar motor neurons in ALS model mice. 2018 Oct 7
36 29746568 The protective effect of the EP2 receptor on TGF-β1 induced podocyte injury via the PI3K / Akt signaling pathway. 2018 1
37 29934349 Prostaglandin Signaling Governs Spike Timing-Dependent Plasticity at Sensory Synapses onto Mouse Spinal Projection Neurons. 2018 Jul 25 1
38 30027346 The renal vasodilatory effect of prostaglandins is ameliorated in isolated-perfused kidneys of endotoxemic mice. 2018 Nov 1
39 30038227 Contribution of prostanoid FP receptor and prostaglandins in transient inflammatory ocular hypertension. 2018 Jul 23 1
40 30371325 Prostaglandin E2 Receptor 2 Modulates Macrophage Activity for Cardiac Repair. 2018 Oct 2 1
41 26746866 Cerebroprotection by the neuronal PGE2 receptor EP2 after intracerebral hemorrhage in middle-aged mice. 2017 Jan 1
42 28062696 Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1. 2017 Feb 15 1
43 28123585 Host knockout of E-prostanoid 2 receptors reduces tumor growth and causes major alterations of gene expression in prostaglandin E2-producing tumors. 2017 Jan 3
44 28174280 Prostaglandin E2-EP2-NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms. 2017 Feb 7 1
45 28281561 EP2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis. 2017 Mar 10 1
46 28341741 Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. 2017 May 19 1
47 28592915 Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines. 2017 1
48 28716915 Prostaglandin dehydrogenase is a target for successful induction of cervical ripening. 2017 Aug 1 1
49 28966102 Prostaglandin E2 facilitates neurite outgrowth in a motor neuron-like cell line, NSC-34. 2017 Oct 3
50 29259703 Prostaglandin E2-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment. 2017 1