Serine

alanine--glyoxylate and serine--pyruvate aminotransferase ; Homo sapiens







27 Article(s)
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1 34838542 1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase. 2022 Jan 2
2 34851798 Human Rhinovirus Infection of the Respiratory Tract Affects Sphingolipid Synthesis. 2022 Mar 1
3 35625596 Alanine-Glyoxylate Aminotransferase Sustains Cancer Stemness Properties through the Upregulation of SOX2 and OCT4 in Hepatocellular Carcinoma Cells. 2022 May 5 2
4 33558762 Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. 2021 Mar 1
5 34059824 Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis. 2021 Jul 4
6 34148472 Identification of a novel SPT inhibitor WXP-003 by docking-based virtual screening and investigation of its anti-fungi effect. 2021 Dec 1
7 34302797 The role of the 'sphingoid motif' in shaping the molecular interactions of sphingolipids in biomembranes. 2021 Nov 1 2
8 34806508 Involvement of Sphingolipid Metabolism Enzymes in Resveratrol-Mediated Cytotoxicity in Philadelphia-Positive Acute Lymphoblastic Leukemia. 2021 Nov 22 1
9 33424845 ORMDL3 and Asthma: Linking Sphingolipid Regulation to Altered T Cell Function. 2020 1
10 30792183 Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase. 2019 May 8
11 31487557 Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. 2019 Dec 1
12 31509666 Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. 2019 Oct 10 1
13 23207405 Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet. 2013 Aug 2
14 24055001 Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase. 2013 Dec 1
15 21558762 Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase. 2011 2
16 21710479 PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism. 2011 Sep 1
17 19346561 Multifunctional role of His159in the catalytic reaction of serine palmitoyltransferase. 2009 Jun 5 3
18 19376777 The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics. 2009 Jun 19 2
19 19887726 Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity. 2009 Oct 5
20 18492492 Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis. 2008 Sep 2
21 16210380 Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. 2005 Nov 15 1
22 12704216 Characterization of serine palmitoyltransferase in normal human tissues. 2003 May 2
23 12782147 Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. 2003 Jun 10 2
24 11085934 The peroxisomal targeting sequence type 1 receptor, Pex5p, and the peroxisomal import efficiency of alanine:glyoxylate aminotransferase. 2000 Dec 1 2
25 11330044 Primary hyperoxaluria type 1 in Japan. 2000 1
26 8245128 ATP-dependent degradation of a mutant serine: pyruvate/alanine:glyoxylate aminotransferase in a primary hyperoxaluria type 1 case. 1993 Dec 1
27 2246616 Serine-palmitoyl transferase activity in cultured human keratinocytes. 1990 Sep 1