Serine

RELA proto-oncogene, NF-kB subunit ; Homo sapiens







184 Article(s)
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1 35265200 HDAC5 modulates PD-L1 expression and cancer immunity via p65 deacetylation in pancreatic cancer. 2022 1
2 35269913 Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP. 2022 Mar 2 2
3 35412596 Case Report And Review Of The Literature: Immune Dysregulation In A Large Familial Cohort Due To A Novel Pathogenic RELA Variant. 2022 Apr 12 2
4 33486415 HJC0416 Attenuates Fibrogenesis in Activated Hepatic Stellate Cells via STAT3 and NF-κB Pathways. 2021 May 1
5 33895704 Substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues potently inhibit respiratory syncytial virus (RSV) replication and RSV infection-associated inflammatory responses. 2021 Jun 1 2
6 31626956 Knockdown of DEAD-box RNA helicase DDX5 selectively attenuates serine 311 phosphorylation of NF-κB p65 subunit and expression level of anti-apoptotic factor Bcl-2. 2020 Jan 1
7 30503244 Activation of Aryl Hydrocarbon Receptor Negatively Regulates Thymic Stromal Lymphopoietin Gene Expression via Protein Kinase Cδ-p300-NF-κB Pathway in Keratinocytes under Inflammatory Conditions. 2019 May 1
8 30527665 Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression. 2019 Jan 3 1
9 30828266 Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone. 2019 1
10 30851634 Both knock-down and overexpression of Rap2a small GTPase in macrophages result in impairment of NF-κB activity and inflammatory gene expression. 2019 May 1
11 31026442 Protein kinase D3 promotes gastric cancer development through p65/6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 activation of glycolysis. 2019 Jul 15 1
12 31580526 Oncogenic Ras mutant causes the hyperactivation of NF-κB via acceleration of its transcriptional activation. 2019 Nov 2
13 28431901 Clozapine reduces Toll-like receptor 4/NF-κB-mediated inflammatory responses through inhibition of calcium/calmodulin-dependent Akt activation in microglia. 2018 Feb 2 2
14 29378189 JN-2, a C-X-C motif chemokine receptor 3 antagonist, ameliorates arthritis progression in an animal model. 2018 Mar 15 1
15 29567473 Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment. 2018 May 5 1
16 28381553 Functional and biochemical characterization of a T cell-associated anti-apoptotic protein, GIMAP6. 2017 Jun 2 1
17 28416608 Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation. 2017 Jun 2 5
18 26613980 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes. 2016 Jan 1
19 26826124 T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium Entry. 2016 Apr 15 1
20 26910425 Binding of NFκB Appears to Twist the Ankyrin Repeat Domain of IκBα. 2016 Feb 23 1
21 27098354 Selective activation of TNFR1 and NF-κB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells. 2016 Apr 20 1
22 27555662 Negative regulation of NF-κB p65 activity by serine 536 phosphorylation. 2016 Aug 23 2
23 27745655 Bisphenol A exposure alters release of immune and developmental modulators and expression of estrogen receptors in human fetal lung fibroblasts. 2016 Oct 1
24 27793942 A Novel Aziridine-based Bruton's Tyrosine Kinase Inhibitor Induces Apoptosis Through Down-regulation of p65/RelA Phosphorylation on Serine 536 and ERK1/2 in Mantle Cell Lymphoma. 2016 Nov 4
25 25450975 Downregulation of diacylglycerol kinase ζ enhances activation of cytokine-induced NF-κB signaling pathway. 2015 Feb 1
26 25520509 Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection. 2015 Mar 2
27 25862606 Simultaneous assessment of NF-κB/p65 phosphorylation and nuclear localization using imaging flow cytometry. 2015 Aug 3
28 25974126 NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells. 2015 1
29 26044852 IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α expression in monocytes: Implications for chronic obstructive pulmonary disease. 2015 Sep 1
30 26082493 Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation. 2015 Aug 14 4
31 26165401 Suppression of casein kinase 2 sensitizes tumor cells to antitumor TRAIL therapy by regulating the phosphorylation and localization of p65 in prostate cancer. 2015 Sep 1
32 26198031 TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP. 2015 Oct 1
33 26246800 Dimethylfumarate protects against TNF-α-induced secretion of inflammatory cytokines in human endothelial cells. 2015 3
34 26693062 IKK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer. 2015 1
35 23812431 PPM1A is a RelA phosphatase with tumor suppressor-like activity. 2014 May 29 1
36 24135685 The NF-κB pathway is rarely spontaneously activated in mantle cell lymphoma (MCL) cell lines and patient's samples. 2014 Jan 2
37 24248603 Role of Ca2+/calmodulin-dependent kinase II-IRAK1 interaction in LMP1-induced NF-κB activation. 2014 Feb 7
38 24337575 Proteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cells. 2014 Jan 31 1
39 24391115 The induction of lipocalin-2 protein expression in vivo and in vitro. 2014 Feb 28 1
40 24574500 Identification of two forms of TNF tolerance in human monocytes: differential inhibition of NF-κB/AP-1- and PP1-associated signaling. 2014 Apr 1 2
41 24582884 Inhibitors of NF-kappaB reverse cellular invasion and target gene upregulation in an experimental model of aggressive oral squamous cell carcinoma. 2014 May 1
42 24621265 Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells. 2014 Aug 2
43 24709138 Toll like receptor-3 priming alters diesel exhaust particle-induced cytokine responses in human bronchial epithelial cells. 2014 Jul 3 1
44 24807716 Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation. 2014 Jul 2
45 24957606 ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment. 2014 Jul 4
46 25201625 AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells. 2014 Jul 24 1
47 22975686 BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB. 2013 Jan 1
48 22996371 Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. 2013 Feb 2
49 23100252 Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment. 2013 Jan 4 2
50 23250755 Phosphorylation of IκBα at serine 32 by T-lymphokine-activated killer cell-originated protein kinase is essential for chemoresistance against doxorubicin in cervical cancer cells. 2013 Feb 1 1