NADP

isocitrate dehydrogenase 2 (NADP+), mitochondrial ; Mus musculus







30 Article(s)
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1 34043997 NADPH supply and the contribution of NAD(P)+ transhydrogenase (NNT) to H2O2 balance in skeletal muscle mitochondria. 2021 Aug 15 1
2 34289383 Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. 2021 Sep 16 3
3 32015410 Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue. 2020 Feb 6
4 32089268 Down-regulation of IDH2 sensitizes cancer cells to erastin-induced ferroptosis. 2020 Apr 30 1
5 32764267 IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle. 2020 Aug 5 2
6 30292083 Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine. 2019 Jan 1
7 30508699 Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency. 2019 Jan 3
8 31064654 IDH2 protects against nonalcoholic steatohepatitis by alleviating dyslipidemia regulated by oxidative stress. 2019 Jun 30 4
9 31121248 IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis. 2019 Sep 1 1
10 31479775 IDH2 deficiency increases bone mass with reduced osteoclastogenesis by limiting RANKL expression in osteoblasts. 2019 Dec 1
11 31546946 Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice. 2019 Sep 19 2
12 29391208 Isocitrate dehydrogenase 2 deficiency exacerbates dermis damage by ultraviolet-B via ΔNp63 downregulation. 2018 Apr 2
13 29567975 Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. 2018 Mar 22 5
14 29660504 IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis. 2018 Jul 1
15 29695796 Mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells. 2018 May 1 1
16 29861476 IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice. 2018 May 27 1
17 30072100 Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-mediated mitochondrial oxidative stress. 2018 Sep 10 2
18 28554049 Increased susceptibility of IDH2-deficient mice to dextran sodium sulfate-induced colitis. 2017 Oct 1
19 28852116 Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics. 2017 Aug 29 2
20 28928092 Idh2 deficiency accelerates renal dysfunction in aged mice. 2017 Nov 4 1
21 29456784 Idh2 Deficiency Exacerbates Acrolein-Induced Lung Injury through Mitochondrial Redox Environment Deterioration. 2017 1
22 27087448 IDH2 knockdown sensitizes tumor cells to emodin cytotoxicity in vitro and in vivo. 2016 Oct 1
23 25557279 IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice. 2015 Mar 2
24 26589116 Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle. 2015 Dec 1
25 24240089 Suppression of tumorigenesis in mitochondrial NADP(+)-dependent isocitrate dehydrogenase knock-out mice. 2014 Feb 2
26 25086359 Mitochondrial NADP(+)-dependent isocitrate dehydrogenase knockdown inhibits tumorigenicity of melanoma cells. 2014 Aug 22 1
27 22416140 SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status. 2012 Apr 20 1
28 21094524 Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. 2010 Nov 24 2
29 17157192 Oxalomalate regulates ionizing radiation-induced apoptosis in mice. 2007 Jan 1 2
30 15586883 Role of NADP+-dependent isocitrate dehydrogenase (NADP+-ICDH) on cellular defence against oxidative injury by gamma-rays. 2004 Sep 3