| 1 |
34520742 | FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication. | 2022 May 19 |
1 |
| 2 |
34937850 | New understandings of the pathway of long-chain polyunsaturated fatty acid biosynthesis. | 2022 Mar 1 |
2 |
| 3 |
35300779 | [Research Progress of Fatty Acid Desaturase 2 Gene in Glycolipid Metabolism]. | 2022 Feb |
8 |
| 4 |
32851475 | Novel carfilzomib-based combinations as potential therapeutic strategies for liposarcomas. | 2021 Feb |
1 |
| 5 |
33310680 | Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans. | 2021 Jan |
1 |
| 6 |
33567271 | Apocryphal FADS2 activity promotes fatty acid diversification in cancer. | 2021 Feb 9 |
1 |
| 7 |
33904180 | Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. | 2021 Jun |
1 |
| 8 |
34143495 | Relaxin has beneficial effects on liver lipidome and metabolic enzymes. | 2021 Jul |
1 |
| 9 |
34303883 | The aromatase inhibitor letrozole restores FADS2 function in ER+ MCF7 human breast cancer cells. | 2021 Aug |
1 |
| 10 |
34740033 | Alterations in hepatic fatty acids reveal depletion of total polyunsaturated fatty acids following irinotecan plus 5-fluorouracil treatment in an animal model of colorectal cancer. | 2021 Nov |
1 |
| 11 |
35211495 | Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and FADS Genetic Variation. | 2021 |
1 |
| 12 |
31751799 | Fatty acid desaturase 2 (FADS2) but not FADS1 desaturates branched chain and odd chain saturated fatty acids. | 2020 Mar |
4 |
| 13 |
31797636 | Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data. | 2020 |
1 |
| 14 |
32365195 | Disturbance of Fatty Acid Desaturation Mediated by FADS2 in Mesenteric Adipocytes Contributes to Chronic Inflammation of Crohn's Disease. | 2020 Nov 7 |
1 |
| 15 |
32381429 | High-throughput transcriptome and pathogenesis analysis of clinical psoriasis. | 2020 May |
1 |
| 16 |
32584610 | Association Between Genetic Variants in FADS1-FADS2 and ELOVL2 and Obesity, Lipid Traits, and Fatty Acids in Tunisian Population. | 2020 Jan-Dec |
2 |
| 17 |
32731631 | Desaturase Activity and the Risk of Type 2 Diabetes and Coronary Artery Disease: A Mendelian Randomization Study. | 2020 Jul 28 |
1 |
| 18 |
33011673 | FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study. | 2020 Nov |
2 |
| 19 |
30082751 | FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression. | 2019 Aug |
1 |
| 20 |
30654845 | Liver DNA methylation of FADS2 associates with FADS2 genotype. | 2019 Jan 17 |
1 |
| 21 |
30814093 | Uncovering Plasticity in Tumor Lipid Metabolism. | 2019 Apr |
1 |
| 22 |
31030467 | Association of Delta-6-Desaturase Expression with Aggressiveness of Cancer, Diabetes Mellitus, and Multiple Sclerosis: A Narrative Review | 2019 Apr 29 |
1 |
| 23 |
31433740 | FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on Health. | 2019 Aug 21 |
1 |
| 24 |
31567872 | FADS1 and FADS2 polymorphism are associated with changes in fatty acid concentrations after calorie-restricted Central European and Mediterranean diets. | 2019 Dec |
1 |
| 25 |
29246731 | A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia. | 2018 Mar - Apr |
1 |
| 26 |
29514873 | Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. | 2018 Jul |
1 |
| 27 |
30103922 | F2-isoprostanes and fatty acids profile in early pregnancy complicated by pre-existing diabetes. | 2018 Aug |
2 |
| 28 |
30157936 | FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression. | 2018 Aug 29 |
1 |
| 29 |
26597785 | Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation. | 2016 Feb |
2 |
| 30 |
27004414 | Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease. | 2016 Mar 22 |
1 |
| 31 |
25497832 | Three unsaturated fatty acid biosynthesis-related genes in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, tissue expression and transcriptional regulation by leptin. | 2015 May 25 |
2 |
| 32 |
26065859 | The fatty acid desaturase 2 (FADS2) gene product catalyzes Δ4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells. | 2015 Sep |
4 |
| 33 |
26087436 | Effect of seafood mediated PCB exposure on desaturase activity and PUFA profile in Faroese septuagenarians. | 2015 Jul |
1 |
| 34 |
26455892 | Genetic and epigenetic transgenerational implications related to omega-3 fatty acids. Part II: maternal FADS2 rs174575 genotype and DNA methylation predict toddler cognitive performance. | 2015 Nov |
2 |
| 35 |
26474818 | Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study. | 2015 Dec |
1 |
| 36 |
24284026 | Delta-6-desaturase links polyunsaturated fatty acid metabolism with phospholipid remodeling and disease progression in heart failure. | 2014 Jan |
2 |
| 37 |
24460221 | Unsaturated fatty acids, desaturases, and human health. | 2014 Feb |
1 |
| 38 |
24847668 | Relationship between estimated fatty acid desaturase activities and abdominal adiposity in Japanese children. | 2014 May-Jun |
2 |
| 39 |
25122663 | Plasma phospholipid fatty acid biomarkers of dietary fat quality and endogenous metabolism predict coronary heart disease risk: a nested case-control study within the Women's Health Initiative observational study. | 2014 Aug 13 |
1 |
| 40 |
25549244 | Loss of FADS2 function severely impairs the use of HeLa cells as an in vitro model for host response studies involving fatty acid effects. | 2014 |
1 |
| 41 |
23221573 | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 Jan |
1 |
| 42 |
23419767 | Abdominal adiposity is associated with fatty acid desaturase activity in boys: implications for C-reactive protein and insulin resistance. | 2013 Apr |
2 |
| 43 |
23667444 | Genetic variation in FADS genes and plasma cholesterol levels in 2-year-old infants: KOALA Birth Cohort Study. | 2013 |
1 |
| 44 |
23737301 | A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems. | 2013 Jul |
1 |
| 45 |
23826354 | FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain. | 2013 |
1 |
| 46 |
24067669 | Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age. | 2013 Dec |
1 |
| 47 |
24294133 | Transcriptional regulation of Δ6-desaturase by peroxisome proliferative-activated receptor δ agonist in human pancreatic cancer cells: role of MEK/ERK1/2 pathway. | 2013 |
2 |
| 48 |
24391980 | A more desirable balanced polyunsaturated fatty acid composition achieved by heterologous expression of Δ15/Δ4 desaturases in mammalian cells. | 2013 |
1 |
| 49 |
22503634 | Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids. | 2012 May 4 |
1 |
| 50 |
22619218 | A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids. | 2012 Aug |
1 |