Methotrexate

solute carrier family 46 member 1 ; Homo sapiens







18 Article(s)
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1 33737637 Folate transporter dynamics and therapy with classic and tumor-targeted antifolates. 2021 Mar 18 1
2 34619546 Functional role of serine 318 of the proton-coupled folate transporter in methotrexate transport. 2021 Dec 1
3 32295203 RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier. 2020 Apr 14 7
4 32893190 A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation. 2020 Nov 13 1
5 31167838 Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways. 2019 Aug 1
6 27649261 MiR-pharmacogenetics of methotrexate in childhood B-cell acute lymphoblastic leukemia. 2016 Nov 2
7 26190800 Methotrexate influx via folate transporters into alveolar epithelial cell line A549. 2015 Aug 2
8 24695276 Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter. 2014 3
9 25124723 SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. 2014 Nov 1
10 23881211 The membrane transport and polyglutamation of pralatrexate: a new-generation dihydrofolate reductase inhibitor. 2013 Sep 2
11 22345511 A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding. 2012 May 1 3
12 19762432 The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs. 2010 Feb 2
13 20610887 Stereoselective transport of amethopterin enantiomers by the proton-coupled folate transporter. 2010 14
14 18823045 Molecular and functional characteristics of proton-coupled folate transporter. 2009 May 3
15 19403800 Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1. 2009 Jul 4
16 19671745 Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line. 2009 Aug 1
17 18559978 A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function. 2008 Sep 1 2
18 17475902 Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. 2007 Aug 10