45 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34750860 | Prefrontal cortex pyramidal neurons express functional Nav1.8 tetrodotoxin-resistant sodium currents. | 2022 Mar | 7 |
2 | 34958174 | A phase I, randomized, double-blind, placebo-controlled, single- and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX-128, a highly selective Nav 1.8 inhibitor, in healthy adults. | 2022 Apr | 1 |
3 | 35092938 | Generation of homozygous Nav1.8 knock-out iPSC lines by CRISPR Cas9 genome editing to investigate a potential new antiarrhythmic strategy. | 2022 Apr | 1 |
4 | 35436748 | Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain. | 2022 Jun 1 | 1 |
5 | 35448095 | Lipopolysaccharide Modifies Sodium Current Kinetics through ROS and PKC Signalling in Induced Pluripotent Stem-Derived Cardiomyocytes from Brugada Syndrome Patient. | 2022 Apr 15 | 1 |
6 | 32686994 | In silico analysis of polyphenols and flavonoids for design of human Nav1.7 inhibitors. | 2021 Aug | 2 |
7 | 33130390 | Structural and dynamical effects of targeted mutations on μO-Conotoxin MfVIA: Molecular simulation studies. | 2021 Jan | 1 |
8 | 33315536 | Functional modulation of the human voltage-gated sodium channel NaV1.8 by auxiliary β subunits. | 2021 Dec | 1 |
9 | 33775738 | Pain behavior in SCN9A (Nav1.7) and SCN10A (Nav1.8) mutant rodent models. | 2021 May 14 | 1 |
10 | 33782571 | The physiological function of different voltage-gated sodium channels in pain. | 2021 May | 1 |
11 | 34222704 | E44Q mutation in NaV1.7 in a patient with infantile paroxysmal knee pain: electrophysiological analysis of voltage-dependent sodium current. | 2021 Jun | 1 |
12 | 34312669 | Common variants in SCN10A gene associated with Brugada syndrome. | 2021 Dec 27 | 1 |
13 | 34389319 | The insecticide deltamethrin enhances sodium channel slow inactivation of human Nav1.9, Nav1.8 and Nav1.7. | 2021 Oct 1 | 1 |
14 | 34758144 | The widely used antihistamine mepyramine causes topical pain relief through direct blockade of nociceptor sodium channels. | 2021 Dec | 1 |
15 | 34782600 | Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure. | 2021 Nov 15 | 1 |
16 | 34827446 | Challenges in Treating Charcot-Marie-Tooth Disease and Related Neuropathies: Current Management and Future Perspectives. | 2021 Oct 29 | 1 |
17 | 32045596 | Upregulation of transcription factor 4 downregulates NaV1.8 expression in DRG neurons and prevents the development of rat inflammatory and neuropathic hypersensitivity. | 2020 May | 1 |
18 | 32078054 | Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice. | 2020 Feb 20 | 2 |
19 | 32295642 | Taxane-induced sensory peripheral neuropathy is associated with an SCN9A single nucleotide polymorphism in Japanese patients. | 2020 Apr 16 | 1 |
20 | 32429423 | Conserved Expression of Nav1.7 and Nav1.8 Contribute to the Spontaneous and Thermally Evoked Excitability in IL-6 and NGF-Sensitized Adult Dorsal Root Ganglion Neurons In Vitro. | 2020 May 16 | 1 |
21 | 32431783 | Do age-associated changes of voltage-gated sodium channel isoforms expressed in the mammalian heart predispose the elderly to atrial fibrillation? | 2020 Apr 26 | 1 |
22 | 32529312 | Repurposing the Dihydropyridine Calcium Channel Inhibitor Nicardipine as a Nav1.8 Inhibitor In Vivo for Pitt Hopkins Syndrome. | 2020 Jun 11 | 1 |
23 | 32550094 | Cannabinoid-Induced Brugada Syndrome: A Case Report. | 2020 Jun 14 | 1 |
24 | 32687732 | Dual mechanism of modulation of NaV1.8 sodium channels by ouabain. | 2020 Nov | 1 |
25 | 32758497 | μ-conotoxin TsIIIA, a peptide inhibitor of human voltage-gated sodium channel hNav1.8. | 2020 Oct 30 | 2 |
26 | 32948286 | Pathogenic mutations perturb calmodulin regulation of Nav1.8 channel. | 2020 Nov 26 | 3 |
27 | 33110213 | Status of peripheral sodium channel blockers for non-addictive pain treatment. | 2020 Dec | 1 |
28 | 33185386 | Early Over-Expressing of microRNA-145 Effectively Precludes the Development of Neuropathic Mechanical Hyperalgesia via Suppressing Nav1.8 in Diabetic Rats. | 2020 Nov | 1 |
29 | 30860870 | Magi-1 scaffolds NaV1.8 and Slack KNa channels in dorsal root ganglion neurons regulating excitability and pain. | 2019 Jun | 1 |
30 | 31481024 | Altered excitability of small cutaneous nerve fibers during cooling assessed with the perception threshold tracking technique. | 2019 Sep 3 | 1 |
31 | 31564962 | Voltage gated sodium channels as therapeutic targets for chronic pain. | 2019 | 1 |
32 | 29752399 | Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction. | 2018 May | 1 |
33 | 29970412 | Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9. | 2018 Aug 6 | 1 |
34 | 30177317 | Sudden cardiac death in J wave syndrome with short QT associated to a novel mutation in Nav 1.8 coding gene SCN10A: First case report for a possible pharmacogenomic role. | 2018 Sep - Oct | 1 |
35 | 25842276 | Novel SCN10A variants associated with Brugada syndrome. | 2016 Jun | 1 |
36 | 25053638 | SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation. | 2014 Nov 1 | 2 |
37 | 23139220 | Neonatal maternal deprivation sensitizes voltage-gated sodium channel currents in colon-specific dorsal root ganglion neurons in rats. | 2013 Feb 15 | 1 |
38 | 23382806 | Varicella-zoster viruses associated with post-herpetic neuralgia induce sodium current density increases in the ND7-23 Nav-1.8 neuroblastoma cell line. | 2013 | 1 |
39 | 22750882 | Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. | 2012 Jul 1 | 1 |
40 | 22870192 | Association between tetrodotoxin resistant channels and lipid rafts regulates sensory neuron excitability. | 2012 | 1 |
41 | 22087007 | Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype. | 2011 Nov 29 | 2 |
42 | 19371587 | Functional and pharmacological properties of human and rat NaV1.8 channels. | 2009 Apr | 1 |
43 | 15703401 | Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA. | 2005 Feb 9 | 1 |
44 | 16325806 | Analysis of human Nav1.8 expressed in SH-SY5Y neuroblastoma cells. | 2005 Dec 28 | 1 |
45 | 9839820 | A tetrodotoxin-resistant voltage-gated sodium channel from human dorsal root ganglia, hPN3/SCN10A. | 1998 Nov | 1 |