| 1 |
31970984 | High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1. | 2020 Feb 19 |
2 |
| 2 |
25071181 | EGF receptor uses SOS1 to drive constitutive activation of NFκB in cancer cells. | 2014 Aug 12 |
1 |
| 3 |
21851854 | Regulation of hSos1 activity is a system-level property generated by its multi-domain structure. | 2012 Jan-Feb |
2 |
| 4 |
22360309 | Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner. | 2012 Mar 13 |
1 |
| 5 |
21779500 | Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives. | 2011 Mar |
1 |
| 6 |
20525880 | Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association. | 2010 Sep |
1 |
| 7 |
17143282 | Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome. | 2007 Jan |
1 |
| 8 |
17586837 | SOS1 is the second most common Noonan gene but plays no major role in cardio-facio-cutaneous syndrome. | 2007 Oct |
1 |
| 9 |
16868024 | Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells. | 2006 Aug 15 |
1 |
| 10 |
17084389 | Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577. | 2006 Nov 27 |
1 |
| 11 |
11524436 | An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. | 2001 Sep 3 |
4 |
| 12 |
11560935 | Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors. | 2001 Dec 14 |
1 |
| 13 |
10938118 | Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development. | 2000 Sep |
1 |
| 14 |
11003655 | Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases. | 2000 Oct |
1 |
| 15 |
10208427 | Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1. | 1999 Mar 4 |
2 |
| 16 |
9447984 | Regulation of Sos activity by intramolecular interactions. | 1998 Feb |
4 |
| 17 |
8577724 | Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. | 1996 Feb 6 |
1 |
| 18 |
8077219 | Prenylation of Ras proteins is required for efficient hSOS1-promoted guanine nucleotide exchange. | 1994 Sep 9 |
7 |
| 19 |
8493579 | Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. | 1993 May 28 |
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