Metals

antioxidant 1 copper chaperone ; Homo sapiens







55 Article(s)
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1 32748830 An EPR Study on the Interaction between the Cu(I) Metal Binding Domains of ATP7B and the Atox1 Metallochaperone. 2020 Aug 2 1
2 30812058 Mass spectrometric quantification of the binding ratio of metal-based anticancer complexes with protein thiols. 2019 May 30 2
3 31187846 The pivotal role of MBD4-ATP7B in the human Cu(i) excretion path as revealed by EPR experiments and all-atom simulations. 2019 Jul 17 1
4 31283225 Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs. 2019 Jul 31 1
5 31341214 Soluble and membrane-bound protein carrier mediate direct copper transport to the ethylene receptor family. 2019 Jul 24 2
6 28027931 Copper chaperone Atox1 plays role in breast cancer cell migration. 2017 Jan 29 1
7 28383086 Platinum transfer from hCTR1 to Atox1 is dependent on the type of platinum complex. 2017 May 24 1
8 28549213 Binding of Copper and Cisplatin to Atox1 Is Mediated by Glutathione through the Formation of Metal-Sulfur Clusters. 2017 Jun 20 1
9 28900031 The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics. 2017 Nov 3 1
10 26797276 Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B. 2016 Feb 12 1
11 26879543 Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway. 2016 Feb 16 1
12 27305454 Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization. 2016 Jul 5 2
13 25673218 Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro. 2015 Jun 1
14 26013029 Enthalpy-entropy compensation at play in human copper ion transfer. 2015 May 27 1
15 24789146 Cisplatin handover between copper transporters: the effect of reducing agents. 2014 Jun 1
16 24824562 T versus D in the MTCXXC motif of copper transport proteins plays a role in directional metal transport. 2014 Aug 2
17 23249252 An expanding range of functions for the copper chaperone/antioxidant protein Atox1. 2013 Sep 20 2
18 23751120 Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. 2013 Aug 15 1
19 23926594 Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains. 2013 Sep 21 1
20 23936210 Determinants for simultaneous binding of copper and platinum to human chaperone Atox1: hitchhiking not hijacking. 2013 1
21 23978201 Investigating the electronic structure of the Atox1 copper(I) transfer mechanism with density functional theory. 2013 Sep 16 2
22 24056613 Conserved residue modulates copper-binding properties through structural dynamics in human copper chaperone Atox1. 2013 Nov 2
23 22574136 In vitro thermodynamic dissection of human copper transfer from chaperone to target protein. 2012 3
24 22578168 Dynamic multibody protein interactions suggest versatile pathways for copper trafficking. 2012 May 30 1
25 23075277 Dynamics and stability of the metal binding domains of the Menkes ATPase and their interaction with metallochaperone HAH1. 2012 Nov 6 1
26 21258123 Unification of the copper(I) binding affinities of the metallo-chaperones Atx1, Atox1, and related proteins: detection probes and affinity standards. 2011 Apr 1 1
27 21322478 Relating dynamic protein interactions of metallochaperones with metal transfer at the single-molecule level. 2011 1
28 21323310 Copper trafficking mechanism of CXXC-containing domains: insight from the pH-dependence of their Cu(I) affinities. 2011 Mar 9 1
29 21482801 Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro. 2011 Apr 26 5
30 21916472 Designed to dissolve: suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperone. 2011 Oct 12 1
31 21981264 Probing the interaction of cisplatin with the human copper chaperone Atox1 by solution and in-cell NMR spectroscopy. 2011 Nov 16 1
32 20166696 Copper-transfer mechanism from the human chaperone Atox1 to a metal-binding domain of Wilson disease protein. 2010 Mar 18 2
33 20726513 Visualizing the metal-binding versatility of copper trafficking sites . 2010 Sep 14 1
34 19181666 An NMR study of the interaction of the N-terminal cytoplasmic tail of the Wilson disease protein with copper(I)-HAH1. 2009 Apr 3 1
35 19453293 Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces. 2009 Jul 29 3
36 19863064 Lysine-60 in copper chaperone Atox1 plays an essential role in adduct formation with a target Wilson disease domain. 2009 Nov 18 2
37 18558714 Metal binding domains 3 and 4 of the Wilson disease protein: solution structure and interaction with the copper(I) chaperone HAH1. 2008 Jul 15 1
38 18685091 Conserved residues modulate copper release in human copper chaperone Atox1. 2008 Aug 12 2
39 17545667 The different intermolecular interactions of the soluble copper-binding domains of the menkes protein, ATP7A. 2007 Aug 10 3
40 16732294 The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction. 2006 Jul 1
41 16813414 Model peptides based on the binding loop of the copper metallochaperone Atx1: selectivity of the consensus sequence MxCxxC for metal ions Hg(II), Cu(I), Cd(II), Pb(II), and Zn(II). 2006 Jul 10 1
42 16873374 Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein. 2006 Sep 29 2
43 14754885 The N-terminal metal-binding site 2 of the Wilson's Disease Protein plays a key role in the transfer of copper from Atox1. 2004 Apr 9 3
44 15134922 Copper transfer to the N-terminal domain of the Wilson disease protein (ATP7B): X-ray absorption spectroscopy of reconstituted and chaperone-loaded metal binding domains and their interaction with exogenous ligands. 2004 May 2
45 15530404 Copper-mediated homo-dimerisation for the HAH1 metallochaperone. 2004 Dec 10 1
46 18365072 Comparative analysis of metal binding characteristics of copper chaperone proteins, Atx1 and ATOX1. 2004 2
47 12679332 Kinetic analysis of the interaction of the copper chaperone Atox1 with the metal binding sites of the Menkes protein. 2003 Jun 6 1
48 12029094 Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity. 2002 Aug 2 1
49 11083871 Solution structure of the yeast copper transporter domain Ccc2a in the apo and Cu(I)-loaded states. 2001 Mar 16 1
50 10764731 Energetics of copper trafficking between the Atx1 metallochaperone and the intracellular copper transporter, Ccc2. 2000 Jun 23 5