Irinotecan

BCL2 like 1 ; Homo sapiens







9 Article(s)
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Pub. Year
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1 31056264 A novel mechanism of irinotecan targeting MDM2 and Bcl-xL. 2019 Jun 25 6
2 24173769 Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NF‑κB. 2014 Jan 1
3 20619636 Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL. 2010 Sep 1
4 18609706 Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells. 2008 Jun 28 1
5 17273826 Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model. 2007 Oct 4
6 17609585 Irinotecan activates p53 with its active metabolite, resulting in human hepatocellular carcinoma apoptosis. 2007 Jul 1
7 17666793 Irinotecan-induced apoptosis is inhibited by increased P-glycoprotein expression and decreased p53 in human hepatocellular carcinoma cells. 2007 Aug 2
8 15604280 Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. 2004 Dec 15 1
9 12855666 Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity. 2003 Jul 2