Paclitaxel

BCL2 like 1 ; Homo sapiens







67 Article(s)
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1 34992683 Paclitaxel resistance is mediated by NF-κB on mesenchymal primary breast cancer cells. 2022 Feb 1
2 34608124 Severe cellular stress activates apoptosis independently of p53 in osteosarcoma. 2021 Oct 4 1
3 34903710 The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents. 2021 Dec 13 2
4 32401925 Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. 2020 1
5 32505840 Xiaoaiping injection enhances paclitaxel efficacy in ovarian cancer via pregnane X receptor and its downstream molecules. 2020 Oct 28 1
6 30359947 MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells. 2019 Jan 1
7 30431082 ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel. 2019 Jan 1
8 31462500 Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer. 2019 Nov 2
9 30013393 The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance. 2018 1
10 28441715 Targeting the Bcl-2 family and P-glycoprotein reverses paclitaxel resistance in human esophageal carcinoma cell line. 2017 Jun 2
11 28507307 A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC. 2017 May 15 1
12 28693250 Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death. 2017 Jul 3
13 26995790 Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. 2016 Apr 1
14 27779649 Effect of curcumin and paclitaxel on breast carcinogenesis. 2016 Dec 1
15 28620450 Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning. 2016 1
16 25596561 Mechanism of synergy of BH3 mimetics and paclitaxel in chronic myeloid leukemia cells: Mcl-1 inhibition. 2015 Apr 5 1
17 25811469 Combining paclitaxel with ABT-263 has a synergistic effect on paclitaxel resistant prostate cancer cells. 2015 6
18 24566868 RSF1 is a positive regulator of NF-κB-induced gene expression required for ovarian cancer chemoresistance. 2014 Apr 15 1
19 24621501 Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosis. 2014 3
20 23474708 Inhibition of Hec1 expression enhances the sensitivity of human ovarian cancer cells to paclitaxel. 2013 Apr 1
21 23681233 Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation. 2013 May 16 4
22 23802633 BCL2 and BCLxL are key determinants of resistance to antitubulin chemotherapeutics in melanoma cells. 2013 Aug 2
23 22076480 Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction. 2012 Jun 2
24 22433870 Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK). 2012 May 18 2
25 22965228 Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins. 2012 Nov 9 2
26 21220478 Navitoclax enhances the efficacy of taxanes in non-small cell lung cancer models. 2011 Mar 15 1
27 21965726 Paclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIF. 2011 Oct 1
28 20100468 Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase. 2010 Jun 1 1
29 20100569 Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells. 2010 Jun 1
30 19351859 Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1. 2009 Apr 15 1
31 19461204 The role of Bcl-xL and nuclear factor-kappaB in the effect of taxol on the viability of dendritic cells. 2009 Jun 2
32 18281549 Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down-regulates antiapoptotic proteins Bcl-XL and survivin. 2008 Feb 15 4
33 18047955 Optimizing chemotherapy for transitional cell carcinoma by application of bcl-2 and bcl-xL antisense oligodeoxynucleotides. 2007 Nov-Dec 1
34 16188300 Bcl-X(L) is functionally non-equivalent for the regulation of growth and survival in human ovarian cancer cells. 2006 Feb 1
35 16231322 FHIT protein enhances paclitaxel-induced apoptosis in lung cancer cells. 2006 Apr 1 1
36 15661210 Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease. 2005 Feb 2
37 16080463 Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel. 2005 May-Jun 8
38 16243823 Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. 2005 Oct 15 1
39 16275990 A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells. 2005 Nov 2
40 14749477 Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis. 2004 Jan 2
41 14975768 Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells. 2004 Mar 12 4
42 12633850 Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol-induced apoptosis. 2003 Mar 13 3
43 12883037 Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis. 2003 Jul 1
44 14617792 Rituximab (anti-CD20) selectively modifies Bcl-xL and apoptosis protease activating factor-1 (Apaf-1) expression and sensitizes human non-Hodgkin's lymphoma B cell lines to paclitaxel-induced apoptosis. 2003 Nov 1
45 26680929 Differential Sensitivity of Taxol-induced Apoptosis in U2OS and SaOS2 Osteogenic Sarcoma Cells. 2003 Apr 1
46 11857368 Overexpression of BclXL in a human ovarian carcinoma cell line: paradoxic effects on chemosensitivity in vitro versus in vivo. 2002 Feb 20 4
47 12226754 The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. 2002 Sep 19 2
48 12389115 Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells. 2002 Oct 1
49 12452453 Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. 2002 Nov 1
50 11592339 Synergistic interaction between topotecan and microtubule-interfering agents. 2001 Sep 2