17 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34445316 | Suppression of Pyruvate Dehydrogenase Kinase by Dichloroacetate in Cancer and Skeletal Muscle Cells Is Isoform Specific and Partially Independent of HIF-1α. | 2021 Aug 10 | 1 |
2 | 31597953 | Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway. | 2020 Jan | 2 |
3 | 31624634 | GSTZ1 genotypes correlate with dichloroacetate pharmacokinetics and chronic side effects in multiple myeloma patients in a pilot phase 2 clinical trial. | 2019 Dec | 3 |
4 | 28881758 | Suppression of pyruvate dehydrogenase kinase-2 re-sensitizes paclitaxel-resistant human lung cancer cells to paclitaxel. | 2017 Aug 8 | 1 |
5 | 26607904 | Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer. | 2016 Feb 1 | 1 |
6 | 27323896 | Pro-haloacetate Nanoparticles for Efficient Cancer Therapy via Pyruvate Dehydrogenase Kinase Modulation. | 2016 Jun 21 | 1 |
7 | 25601413 | Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate. | 2015 Sep | 2 |
8 | 24747400 | Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. | 2014 May 29 | 1 |
9 | 25482950 | Targeting of two aspects of metabolism in breast cancer treatment. | 2014 | 2 |
10 | 21283817 | Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilization. | 2011 Jan 19 | 1 |
11 | 19147752 | Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. | 2009 Jan 15 | 1 |
12 | 19833728 | Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate. | 2009 Dec 4 | 3 |
13 | 18627174 | Allosteric coupling in pyruvate dehydrogenase kinase 2. | 2008 Aug 12 | 1 |
14 | 17222789 | A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. | 2007 Jan | 1 |
15 | 17544412 | Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2. | 2007 Jun 26 | 3 |
16 | 10748134 | Marked differences between two isoforms of human pyruvate dehydrogenase kinase. | 2000 May 26 | 4 |
17 | 9405293 | Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex. | 1998 Jan 1 | 1 |