Oxaliplatin

solute carrier family 22 member 2 ; Homo sapiens







14 Article(s)
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1 35163014 Role of Organic Cation Transporter 2 in Autophagy Induced by Platinum Derivatives. 2022 Jan 19 4
2 33376510 Silencing GnT-V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N-glycan alteration of organic cation transporter member 2. 2021 Feb 1
3 34252480 L-tetrahydropalmatine reduces oxaliplatin accumulation in the dorsal root ganglion and mitochondria through selectively inhibiting the transporter-mediated uptake thereby attenuates peripheral neurotoxicity. 2021 Jul 1
4 32206108 The failure of DAC to induce OCT2 expression and its remission by hemoglobin-based nanocarriers under hypoxia in renal cell carcinoma. 2020 1
5 32484793 Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice. 2020 Sep 1 1
6 29417972 Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells. 2018 Mar 1 4
7 26474693 Celecoxib antagonizes the cytotoxicity of oxaliplatin in human esophageal cancer cells by impairing the drug influx. 2016 Jan 1 4
8 24427340 Organic cation transporter 2 and tumor budding as independent prognostic factors in metastatic colorectal cancer patients treated with oxaliplatin-based chemotherapy. 2014 4
9 25232494 High expression of organic anion transporter 2 and organic cation transporter 2 is an independent predictor of good outcomes in patients with metastatic colorectal cancer treated with FOLFOX-based chemotherapy. 2014 2
10 23776246 Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2. 2013 Jul 2 1
11 20067471 Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2). 2010 Feb 4
12 20551056 Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters. 2010 Jul 15 2
13 16914559 Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family). 2006 Nov 2
14 16951202 Organic cation transporters are determinants of oxaliplatin cytotoxicity. 2006 Sep 1 3