4-nitrobenzylthioinosine

solute carrier family 29 member 1 (Augustine blood group) ; Homo sapiens







63 Article(s)
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1 33426680 Fluorouracil uptake in triple-negative breast cancer cells: Negligible contribution of equilibrative nucleoside transporters 1 and 2. 2021 Mar 4
2 33980604 Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1. 2021 Jul 4
3 34503974 Remdesivir and EIDD-1931 Interact with Human Equilibrative Nucleoside Transporters 1 and 2: Implications for Reaching SARS-CoV-2 Viral Sanctuary Sites. 2021 Dec 2
4 32313990 Apoptotic and anti-proliferative effect of guanosine and guanosine derivatives in HuT-78 T lymphoma cells. 2020 Jul 1
5 32339528 Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells. 2020 Aug 2
6 32393653 Nucleoside Reverse Transcriptase Inhibitor Interaction with Human Equilibrative Nucleoside Transporters 1 and 2. 2020 Jul 2
7 32635975 Transport of ribavirin in human myelogenous leukemia cell line K562. 2020 Jul 1 1
8 32858046 Intracellular adenosine released from THP-1 differentiated human macrophages is involved in an autocrine control of Leishmania parasitic burden, mediated by adenosine A2A and A2B receptors. 2020 Oct 15 1
9 33105674 Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier. 2020 Oct 22 1
10 31235912 Structures of human ENT1 in complex with adenosine reuptake inhibitors. 2019 Jul 2
11 30214194 Antitumor effect of gemcitabine-loaded albumin nanoparticle on gemcitabine-resistant pancreatic cancer induced by low hENT1 expression. 2018 2
12 30254099 Role of cysteine 416 in N-ethylmaleimide sensitivity of human equilibrative nucleoside transporter 1 (hENT1). 2018 Oct 31 2
13 27995448 Functional characterization of human equilibrative nucleoside transporter 1. 2017 Apr 1
14 28292464 Intracellular acidification increases adenosine transport in human umbilical vein endothelial cells. 2017 Mar 1
15 27480168 N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function. 2016 Aug 4
16 26235575 Cellular Uptake of Decitabine by Equilibrative Nucleoside Transporters in HCT116 Cells. 2015 2
17 23814180 The role of human equilibrative nucleoside transporter 1 on the cellular transport of the DNA methyltransferase inhibitors 5-azacytidine and CP-4200 in human leukemia cells. 2013 Sep 2
18 22232287 ENT1, a ribavirin transporter, plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system. 2012 Mar 1
19 22837314 Cysteine residues in the transmembrane (TM) 9 to TM11 region of the human equilibrative nucleoside transporter subtype 1 play an important role in inhibitor binding and translocation function. 2012 Nov 1
20 21455275 Analysis of recombinant tagged equilibrative nucleoside transporter 1 (ENT1) expressed in E. coli. 2011 Apr 2
21 21791574 Identification of cysteines involved in the effects of methanethiosulfonate reagents on human equilibrative nucleoside transporter 1. 2011 Oct 2
22 21795683 Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1). 2011 Sep 16 1
23 21965724 Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1. 2011 Oct 1
24 19788890 Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine. 2010 Feb 15 3
25 20728214 Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells. 2010 Oct 1
26 20814156 Human erythrocyte nucleoside transporter ENT1 functions at ice-cold temperatures. 2010 5
27 19091561 CoMFA and CoMSIA 3D-QSAR studies on S(6)-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1). 2009 Jan 15 2
28 19116148 Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells. 2009 Jan 22 1
29 19699178 Disrupted plasma membrane localization and loss of function reveal regions of human equilibrative nucleoside transporter 1 involved in structural integrity and activity. 2009 Oct 2
30 18289860 Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. 2008 Apr 1 4
31 18462193 Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity. 2008 Sep 1 3
32 18669604 The role of human nucleoside transporters in uptake of 3'-deoxy-3'-fluorothymidine. 2008 Nov 1
33 17167068 A novel mechanism of vasoregulation: ADP-induced relaxation of the porcine isolated coronary artery is mediated via adenosine release. 2007 Feb 1
34 17379602 Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover. 2007 May 11 2
35 17409283 Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 Jul 1
36 17695509 Human equilibrative nucleoside transporter 1, as a predictor of 5-fluorouracil resistance in human pancreatic cancer. 2007 Jul-Aug 2
37 17881236 Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors. 2007 Dec 15 2
38 16617163 The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine. 2006 Jul 1
39 15634027 Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines. 2005 Jan 13 2
40 15905191 Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment. 2005 Sep 1 1
41 14607828 Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs. 2004 Feb 6 1
42 14759222 Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1. 2004 May 15 4
43 15037197 Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep. 2004 Feb 1 4
44 15149181 Design, synthesis, and evaluation of 5'-S-aminoethyl-N(6)- azidobenzyl-5'-thioadenosine biotin conjugate: a bifunctional photoaffinity probe for the es nucleoside transporter. 2004 May-Jun 1
45 15471562 Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer. 2004 Sep 2
46 15481982 Inhibition of nucleoside transport by new analogues of 4-nitrobenzylthioinosine: replacement of the ribose moiety by substituted benzyl groups. 2004 Oct 21 2
47 12538831 Inhibition of nucleoside transport by protein kinase inhibitors. 2003 Feb 1
48 12820662 Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells. 2003 Apr 1 1
49 11801546 Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers. 2002 Jan 1
50 11814344 A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine. 2002 Feb 5 4