| 1 |
34272713 | Case Study 6: Deconvoluting Hyperbilirubinemia-Differentiating Between Hepatotoxicity and Reversible Inhibition of UGT1A1, MRP2, or OATP1B1 in Drug Development. | 2021 |
1 |
| 2 |
32407928 | Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms. | 2020 Jul 15 |
1 |
| 3 |
25315738 | Gene replacement therapy for genetic hepatocellular jaundice. | 2015 Jun |
1 |
| 4 |
26191226 | Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis. | 2015 |
1 |
| 5 |
26413716 | A GWAS Study on Liver Function Test Using eMERGE Network Participants. | 2015 |
1 |
| 6 |
23886114 | In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia. | 2014 Mar |
1 |
| 7 |
24523126 | Case study 5. Deconvoluting hyperbilirubinemia: differentiating between hepatotoxicity and reversible inhibition of UGT1A1, MRP2, or OATP1B1 in drug development. | 2014 |
1 |
| 8 |
24587300 | Serum bilirubin concentration in healthy adult North-Europeans is strictly controlled by the UGT1A1 TA-repeat variants. | 2014 |
1 |
| 9 |
22982575 | Hereditary conjugated hyperbilirubinaemia: 37 years later. | 2013 Feb |
2 |
| 10 |
23243220 | Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice. | 2013 Feb 15 |
1 |
| 11 |
23371916 | A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population. | 2013 Apr |
3 |
| 12 |
23750830 | Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia. | 2013 Aug 5 |
2 |
| 13 |
24151358 | New insights in bilirubin metabolism and their clinical implications. | 2013 Oct 14 |
1 |
| 14 |
22232210 | Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver. | 2012 Feb |
2 |
| 15 |
22954695 | Loss of OATP1B3 function causes Rotor syndrome: implications for potential use of inhibitors in cancer. | 2012 Dec |
1 |
| 16 |
21615622 | Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma. | 2011 Sep |
1 |
| 17 |
19419973 | Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. | 2009 Jul 15 |
2 |
| 18 |
15535988 | Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia. | 2004 Nov 20 |
1 |
| 19 |
12568656 | Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin. | 2003 May 1 |
1 |