Irinotecan

notch receptor 1 ; Homo sapiens







2 Article(s)
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1 22521243 ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer. 2012 Jun 2
2 19147571 gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. 2009 Jan 15 5