Reactive Oxygen Species

peroxiredoxin 1 ; Homo sapiens







54 Article(s)
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1 35179864 Hepatotoxicity-Related Oxidative Modifications of Thioredoxin 1/Peroxiredoxin 1 Induced by Different Cadmium-Based Quantum Dots. 2022 Mar 1 2
2 33712558 Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer. 2021 Mar 12 2
3 33749526 PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage. 2021 Dec 1
4 33889951 Biallelic loss-of-function variations in PRDX3 cause cerebellar ataxia. 2021 Jun 22 1
5 33907575 Regulatory function of peroxiredoxin I on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer development. 2021 Jun 3
6 34428517 Peroxiredoxin 1 is essential for natamycin-triggered apoptosis and protective autophagy in hepatocellular carcinoma. 2021 Aug 21 5
7 31477836 TXNDC9 regulates oxidative stress-induced androgen receptor signaling to promote prostate cancer progression. 2020 Jan 2
8 32316111 Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells. 2020 Apr 16 1
9 32736685 Peroxiredoxin I deficiency increases keratinocyte apoptosis in a skin tumor model via the ROS-p38 MAPK pathway. 2020 Aug 27 1
10 33011678 A curious case of cysteines in human peroxiredoxin I. 2020 Oct 1
11 33147465 PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage. 2020 Nov 3 1
12 30661989 Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. 2019 Mar 21 2
13 30693924 Organometallic ruthenium anticancer complexes inhibit human peroxiredoxin I activity by binding to and inducing oxidation of its catalytic cysteine residue. 2019 Mar 20 1
14 30871234 Peroxiredoxin6 in Endothelial Signaling. 2019 Mar 13 2
15 30894323 Differential induction of nuclear factor-like 2 signature genes with toll-like receptor stimulation. 2019 May 1 2
16 31485630 Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway. 2019 Nov 5
17 29341349 Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease. 2018 Feb 1
18 29707240 Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway. 2018 5
19 29773556 PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase. 2018 May 1 2
20 30187908 Expression of peroxiredoxins in the human testis, epididymis and spermatozoa and their role in preventing H2O2-induced damage to spermatozoa. 2018 1
21 30588251 Utilization of Reactive Oxygen Species Targeted Therapy to Prolong the Efficacy of BRAF Inhibitors in Melanoma. 2018 1
22 27653015 Peroxiredoxin 1 - an antioxidant enzyme in cancer. 2017 Jan 6
23 28219939 Peroxiredoxin 1 (Prx1) is a dual-function enzyme by possessing Cys-independent catalase-like activity. 2017 Apr 4 3
24 28827763 Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels. 2017 Aug 21 5
25 26528922 Effective Killing of Cancer Cells Through ROS-Mediated Mechanisms by AMRI-59 Targeting Peroxiredoxin I. 2016 Mar 10 1
26 26733168 Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer. 2016 Jun 1
27 27158373 Identification and verification of PRDX1 as an inflammation marker for colorectal cancer progression. 2016 2
28 28009281 Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase. 2016 Dec 20 1
29 25484280 Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress. 2015 Jun 5
30 26169724 Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1. 2015 Dec 2
31 26689287 PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: a potential new therapeutic perspective for an old drug. 2015 Dec 21 2
32 24715692 Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells. 2014 Apr 2
33 26461286 Peroxiredoxin 1 knockdown sensitizes cancer cells to reactive oxygen species-generating drugs - an alternative approach for chemotherapy. 2014 Oct 9
34 23186333 Prx I suppresses K-ras-driven lung tumorigenesis by opposing redox-sensitive ERK/cyclin D1 pathway. 2013 Aug 10 4
35 23239746 Peroxiredoxin 1 knockdown potentiates β-lapachone cytotoxicity through modulation of reactive oxygen species and mitogen-activated protein kinase signals. 2013 Apr 6
36 23334324 Role for Prdx1 as a specific sensor in redox-regulated senescence in breast cancer. 2013 Nov 7 1
37 23933099 Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway. 2013 Nov 15 1
38 22231406 Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins. 2012 Feb 1 4
39 22877757 RNA-binding properties and RNA chaperone activity of human peroxiredoxin 1. 2012 Sep 7 1
40 21468086 Silencing Prx1 and/or Prx5 sensitizes human esophageal cancer cells to ionizing radiation and increases apoptosis via intracellular ROS accumulation. 2011 Apr 2
41 20113375 Glucose transporter protein 1 expression in mucoepidermoid carcinoma of salivary gland: correlation with grade of malignancy. 2010 Apr 1
42 20732753 Role of peroxiredoxin I in rectal cancer and related to p53 status. 2010 Nov 1 1
43 19351539 TAT-mediated peroxiredoxin 5 and 6 protein transduction protects against high-glucose-induced cytotoxicity in retinal pericytes. 2009 Jun 5 2
44 19652395 Proteomic analysis in cyclosporin A-induced overgrowth of human gingival fibroblasts. 2009 Aug 4
45 18452719 Protective effects of peroxiredoxin-1 at the injured blood-brain barrier. 2008 Aug 1 4
46 17211829 Proteome analysis of human macrophages reveals the upregulation of manganese-containing superoxide dismutase after toll-like receptor activation. 2007 Feb 1
47 17234762 Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. 2007 Jan 15 1
48 17909037 Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation. 2007 Oct 1 2
49 16817890 Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA. 2006 Jun 1
50 16849559 Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex. 2006 Jul 15 1