| 1 |
32721527 | Enhanced P-glycoprotein expression under high-altitude hypoxia contributes to increased phenytoin levels and reduced clearance in rats. | 2020 Oct 1 |
4 |
| 2 |
29380527 | The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus. | 2018 Jul |
2 |
| 3 |
27162079 | Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy. | 2016 Aug |
1 |
| 4 |
26649451 | Phenytoin carried by silica core iron oxide nanoparticles reduces the expression of pharmacoresistant seizures in rats. | 2015 |
3 |
| 5 |
23530507 | P-glycoprotein contributes to cell membrane depolarization of hippocampus and neocortex in a model of repetitive seizures induced by pentylenetetrazole in rats. | 2013 |
2 |
| 6 |
24348021 | P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy. | 2013 |
2 |
| 7 |
21640186 | Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in rats. | 2011 Sep 18 |
4 |
| 8 |
19958760 | Exposure to antiepileptic drugs does not alter the functionality of P-glycoprotein in brain capillary endothelial and kidney cell lines. | 2010 Feb 25 |
1 |
| 9 |
20643531 | Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsy. | 2010 Sep |
2 |
| 10 |
18266746 | Development of tolerance to levetiracetam in rats with chronic epilepsy. | 2008 Jul |
3 |
| 11 |
18440557 | Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain. | 2008 Jul 15 |
1 |
| 12 |
18473823 | Induction of nuclear receptors and drug resistance in the brain microvascular endothelial cells treated with antiepileptic drugs. | 2008 May |
2 |
| 13 |
17240061 | Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model. | 2007 Feb 14 |
1 |
| 14 |
17392402 | Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats. | 2007 Jul |
6 |
| 15 |
18330007 | Mechanisms of drug resistance in status epilepticus. | 2007 |
2 |
| 16 |
16650133 | Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats. | 2006 Apr |
4 |
| 17 |
15232302 | Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats. | 2004 Jul 19 |
1 |
| 18 |
15569486 | Antiepileptic drug-induced multidrug resistance P-glycoprotein overexpression in astrocytes cultured from rat brains. | 2004 Nov |
3 |
| 19 |
12231384 | Lack of effects of prolonged treatment with phenobarbital or phenytoin on the expression of P-glycoprotein in various rat brain regions. | 2002 Sep 13 |
3 |
| 20 |
11737157 | In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats. | 2001 Oct |
3 |