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35073698 | N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action. | 2022 Feb 10 |
4 |
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35373257 | The Importance of Drug Concentration at the Site of Action: Celecoxib and Colon Polyp Prevention as a Case Study. | 2022 Apr 1 |
2 |
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34033145 | High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients. | 2021 Jun |
1 |
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33182324 | Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology. | 2020 Nov 9 |
1 |
| 5 |
33396527 | Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility. | 2020 Dec 31 |
1 |
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30191990 | Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment. | 2019 Apr |
2 |
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31231138 | Replacement of an Indole Scaffold Targeting Human 15-Lipoxygenase-1 Using Combinatorial Chemistry. | 2019 May |
2 |
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28757355 | 15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1. | 2017 Nov |
1 |
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26560362 | 15-Lipoxygenase inhibitors: a patent review. | 2016 |
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| 10 |
27832777 | A proteomic analysis of acute leukemia cells treated with 9-hydroxyoctadecadienoic acid. | 2016 Nov 10 |
2 |
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26194111 | The role of 15-LOX-1 in colitis and colitis-associated colorectal cancer. | 2015 Sep |
1 |
| 12 |
22770909 | A strategy for promoting bone regeneration by inducible expression of 15-LOX-1. | 2012 Sep |
1 |
| 13 |
21804214 | Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro. | 2011 |
2 |
| 14 |
22037943 | 15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in? | 2011 Dec |
2 |
| 15 |
17604003 | 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. | 2007 Aug 15 |
1 |
| 16 |
16288226 | Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. | 2006 Feb 23 |
2 |
| 17 |
16166323 | Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells. | 2005 Sep 15 |
1 |
| 18 |
16357157 | The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. | 2005 Dec 15 |
2 |
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12711249 | Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. | 2003 May |
1 |
| 20 |
11406566 | Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. | 2001 Jun 15 |
1 |
| 21 |
11441135 | Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions. | 2001 Jul |
1 |
| 22 |
10802222 | Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. | 2000 Mar 15 |
1 |
| 23 |
10904086 | 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. | 2000 Jul 19 |
1 |
| 24 |
11156377 | 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. | 2000 Dec 15 |
1 |
| 25 |
10400618 | 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. | 1999 Jul 16 |
1 |
| 26 |
10506115 | Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. | 1999 Oct |
1 |
| 27 |
9569236 | Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. | 1998 May |
1 |
| 28 |
9690711 | Regulation of endothelial cell and platelet receptor-ligand binding by the 12- and 15-lipoxygenase monohydroxides, 12-, 15-HETE and 13-HODE. | 1998 May |
1 |
| 29 |
9705287 | Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation. | 1998 Aug 21 |
2 |
| 30 |
9820810 | Omega-oxidation impairs oxidizability of polyenoic fatty acids by 15-lipoxygenases: consequences for substrate orientation at the active site. | 1998 Dec 1 |
1 |
| 31 |
9070230 | Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. | 1997 Feb 3 |
2 |
| 32 |
9355754 | Co-oxidation of NADH and NADPH by a mammalian 15-lipoxygenase: inhibition of lipoxygenase activity at near-physiological NADH concentrations. | 1997 Oct 1 |
1 |
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7829882 | Epidermal fatty acid oxygenases are activated in non-psoriatic dermatoses. | 1995 Feb |
1 |
| 34 |
8577345 | Characterization of arachidonic-acid-metabolizing enzymes in adult Schistisoma mansoni. | 1995 Jul |
1 |
| 35 |
8178971 | 13-HODE increases intracellular calcium in vascular smooth muscle cells. | 1994 Apr |
1 |
| 36 |
1546066 | Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein. | 1992 Jan |
1 |
| 37 |
1632527 | A spectrophotometric microtiter-based assay for the detection of hydroperoxy derivatives of linoleic acid. | 1992 Mar |
2 |
| 38 |
1659156 | Linoleic acid and dihomogammalinolenic acid inhibit leukotriene B4 formation and stimulate the formation of their 15-lipoxygenase products by human neutrophils in vitro. Evidence of formation of antiinflammatory compounds. | 1991 Jul |
1 |
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2318885 | Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related. | 1990 Mar 25 |
1 |
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2459258 | Enzymatic properties of the 15-lipoxygenase of human cultured keratinocytes. | 1988 Oct |
1 |