Alcohols

cytochrome P450, family 2, subfamily e, polypeptide 1 ; Rattus norvegicus







68 Article(s)
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1 34221085 Hepatoprotective Effects of the Cichorium intybus Root Extract against Alcohol-Induced Liver Injury in Experimental Rats. 2021 1
2 34732632 A New Perspective on Fish Oil: The Prevention of Alcoholic Liver Disease. 2021 1
3 32777474 Alcohol suppresses cardiovascular diurnal variations in male normotensive rats: Role of reduced PER2 expression and CYP2E1 hyperactivity in the heart. 2020 Dec 2
4 30362092 Chronic Ethanol Consumption and Generation of Etheno-DNA Adducts in Cancer-Prone Tissues. 2018 1
5 28667748 Combined Catalase and ADH Inhibition Ameliorates Ethanol-Induced Myocardial Dysfunction Despite Causing Oxidative Stress in Conscious Female Rats. 2017 Sep 2
6 29456571 Resveratrol Ameliorates Experimental Alcoholic Liver Disease by Modulating Oxidative Stress. 2017 1
7 27043860 Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression. 2016 Nov 1
8 25262104 Effects of triterpenoid from Schisandra chinensis on oxidative stress in alcohol-induced liver injury in rats. 2015 Mar 2
9 24815155 Γ-glutamyl transferase as an early and sensitive marker in ethanol-induced liver injury of rats. 2014 May 1
10 26202644 Pre-endurance training prevents acute alcoholic liver injury in rats through the regulation of damaged mitochondria accumulation and mitophagy balance. 2014 Jul 1
11 23819932 CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen. 2013 Jun 1
12 21813270 Effects of soy protein on alcoholic liver disease in rats undergoing ethanol withdrawal. 2012 Jun 1
13 21999510 Ethanol induced induction of cytochrome P450 2E1 and activation of mitogen activated protein kinases in peripheral blood lymphocytes. 2012 Apr 2
14 22289614 Amelioration of alcohol-induced hepatotoxicity by the administration of ethanolic extract of Sida cordifolia Linn. 2012 Oct 1
15 22486562 Oxidative stress modulates KLF6Full and its splice variants. 2012 Nov 1
16 23543859 Cytochrome P450 2E1 inhibition prevents hepatic carcinogenesis induced by diethylnitrosamine in alcohol-fed rats. 2012 Dec 3
17 21036165 Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease. 2011 Feb 1
18 21790668 Alcohol induces liver neoplasia in a novel alcohol-preferring rat model. 2011 Dec 2
19 21897050 Depression by a green tea extract of alcohol-induced oxidative stress and lipogenesis in rat liver. 2011 1
20 20529841 Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress. 2010 Aug 6 2
21 18990514 Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell. 2009 Feb 1 1
22 19285975 Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake. 2009 May 1 1
23 20041771 Proteomic analysis of the protective effects of Platycodi Radix in liver of chronically alcoholic rats. 2009 Dec 1
24 18414994 A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1. 2008 Jul 1
25 18567756 High dose lycopene supplementation increases hepatic cytochrome P4502E1 protein and inflammation in alcohol-fed rats. 2008 Jul 2
26 18571270 Prevention of alcoholic fatty liver and mitochondrial dysfunction in the rat by long-chain polyunsaturated fatty acids. 2008 Aug 1
27 17587688 Protective effects of Platycodi radix on alcohol-induced fatty liver. 2007 Jun 3
28 17606256 Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity. 2007 Aug 30 1
29 17681033 Role of medium-chain triglycerides in the alcohol-mediated cytochrome P450 2E1 induction of mitochondria. 2007 Oct 7
30 21469506 Effect of caffeine and alcohol on the toxicity and metabolism of methacrylonitrile in male Sprague-Dawley rats. 2007-2008 1
31 16380384 Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione. 2006 Feb 24 1
32 16487260 Effect of alcohol on cytochrome p450 arachidonic acid metabolism and blood pressure in rats and its modulation by red wine polyphenolics. 2006 Mar 1
33 17058263 Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats. 2006 Nov 1
34 17533807 Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet. 2006 Oct 2
35 12777398 Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. 2003 Aug 8 1
36 12824824 Immunohistochemical characterization of hepatic malondialdehyde and 4-hydroxynonenal modified proteins during early stages of ethanol-induced liver injury. 2003 Jun 1
37 11756226 Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes. 2002 Jan 2
38 11796198 Free radical mechanisms in immune reactions associated with alcoholic liver disease. 2002 Jan 15 2
39 12143040 Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver. 2002 Aug 2
40 12191992 Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation. 2002 Oct 25 2
41 11173972 Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease. 2001 Jan-Feb 1
42 11689017 Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1. 2001 Nov 9 2
43 10640507 Identification of a ubiquitination-Target/Substrate-interaction domain of cytochrome P-450 (CYP) 2E1. 2000 Feb 1
44 10698373 Attenuation of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC). 2000 Feb 1
45 10456581 Reversal of ethanol-induced hepatic steatosis and lipid peroxidation by taurine: a study in rats. 1999 Jul-Aug 1
46 10503926 CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation. 1999 1
47 9871487 Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats. 1998 2
48 9884160 Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A. 1998 Dec 1
49 9023260 Acetaldehyde as well as ethanol is metabolized by human CYP2E1. 1997 Feb 1
50 9187260 Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. 1997 Jun 1