Acetaminophen

cytochrome P450, family 2, subfamily e, polypeptide 1 ; Rattus norvegicus







25 Article(s)
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1 31468699 CYP2E1 and miRNA-378a-3p contribute to acetaminophen- or tripterygium glycosides-induced hepatotoxicity. 2020 Feb 3
2 32132876 Drug-drug interaction of acetaminophen and roxithromycin with the cocktail of cytochrome P450 and hepatotoxicity in rats. 2020 1
3 30556209 Hepatoprotective and antioxidant potential of Pycnogenol® in acetaminophen-induced hepatotoxicity in rats. 2019 Mar 1
4 30794797 Effect of chrysin on the formation of N-acetyl-p-benzoquinoneimine, a toxic metabolite of paracetamol in rats and isolated rat hepatocytes. 2019 Apr 1 3
5 31155811 Quercetin reduced the formation of N-acetyl-p-benzoquinoneimine, a toxic metabolite of paracetamol in rats and isolated rat hepatocytes. 2019 Jul 3
6 30393430 Effects of food restriction on the expression of genes related to acetaminophen-induced liver toxicity in rats. 2018 Oct 1
7 25645193 Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress. 2015 Jul 2
8 25678313 Systemic exposure of Paracetamol (acetaminophen) was enhanced by quercetin and chrysin co-administration in Wistar rats and in vitro model: risk of liver toxicity. 2015 1
9 22870820 Protective effect of fucoidan against acetaminophen-induced liver injury. 2012 Jun 2
10 22011590 Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats. 2011 Oct 20 1
11 19834287 Alteration in metabolism and toxicity of acetaminophen upon repeated administration in rats. 2009 Oct 2
12 18710030 [Effect of diet overloaded by fats on the enzyme systems of metabolism in rats]. 2008 Jan-Feb 1
13 17520838 Interaction between traditional Chinese medicine and Western medicine in rats--In-Chen-How and acetaminophen. 2007 Mar 1
14 17620348 Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation. 2007 Oct 3
15 16797510 Acetaminophen-induced hepatotoxicity of gel entrapped rat hepatocytes in hollow fibers. 2006 Jul 25 1
16 15772367 Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes. 2005 Jun 1
17 16162422 Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats. 2005 Sep 1
18 12143040 Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver. 2002 Aug 2
19 12433812 Effects of ethanol dose and ethanol withdrawal on rat liver mitochondrial glutathione: implication of potentiated acetaminophen toxicity in alcoholics. 2002 Dec 2
20 11162779 Protective effect of stiripentol on acetaminophen-induced hepatotoxicity in rat. 2001 Feb 1 3
21 17694370 The role of calcium in paracetamol (acetaminophen) cytotoxicity in PC12 cells transfected with CYP4502E1. 1998 1
22 8997458 Protection of ethanol-mediated acetaminophen hepatotoxicity by triacetyloleandomycin, a specific inhibitor of CYP3A. 1997 Jan-Feb 4
23 9144448 Role of CYP3A in ethanol-mediated increases in acetaminophen hepatotoxicity. 1997 Apr 1
24 9253715 Acetaminophen metabolism and cytotoxicity in PC12 cells transfected with cytochrome P4502E1. 1997 Jul 2
25 8466546 Zonation of acetaminophen metabolism and cytochrome P450 2E1-mediated toxicity studied in isolated periportal and perivenous hepatocytes. 1993 Mar 24 1