Guanosine Triphosphate

cell division cycle 42 ; Homo sapiens







272 Article(s)
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1 35152498 Molecular dynamics simulations reveal the activation mechanism of mutations G12V and Q61L of Cdc42. 2022 Jul 2
2 35186026 Cdc42/Rac Interactive Binding Containing Effector Proteins in Unicellular Protozoans With Reference to Human Host: Locks of the Rho Signaling. 2022 1
3 35215978 Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? 2022 Feb 14 1
4 35317515 CIP4 targeted to recruit GTP-Cdc42 involving in invadopodia formation via NF-κB signaling pathway promotes invasion and metastasis of CRC. 2022 Mar 17 1
5 35583642 Targeting Cancer by Using Nanoparticles to Modulate RHO GTPase Signaling. 2022 1
6 33347888 Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics. 2021 Jan 19 7
7 33473262 Cdc42 functions as a regulatory node for tumour-derived microvesicle biogenesis. 2021 Jan 1
8 34790187 Cell Division Control Protein 42 Interacts With Hepatitis E Virus Capsid Protein and Participates in Hepatitis E Virus Infection. 2021 4
9 32162745 Cholesterol asymmetry at the tip of filopodia during cell adhesion. 2020 May 2
10 32545340 Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors. 2020 Jun 11 1
11 32548242 A Review on the Function and Regulation of ARHGDIB/RhoGDI2 Expression Including the Hypothetical Role of ARHGDIB/RhoGDI2 Autoantibodies in Kidney Transplantation. 2020 May 1
12 30754684 Focus on Cdc42 in Breast Cancer: New Insights, Target Therapy Development and Non-Coding RNAs. 2019 Feb 11 1
13 30872454 The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity. 2019 Apr 25 1
14 30959099 Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling. 2019 Aug 1
15 31019460 NEDD9 Facilitates Hypoxia-Induced Gastric Cancer Cell Migration via MICAL1 Related Rac1 Activation. 2019 1
16 31330900 The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System. 2019 Jul 21 1
17 31396321 Platelet-rich plasma in combination with adipose-derived stem cells promotes skin wound healing through activating Rho GTPase-mediated signaling pathway. 2019 1
18 28479334 CDC42-related genes are upregulated in helper T cells from obese asthmatic children. 2018 Feb 2
19 29072916 Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion. 2018 Jan 5 2
20 29335451 A hot-spot mutation in CDC42 (p.Tyr64Cys) and novel phenotypes in the third patient with Takenouchi-Kosaki syndrome. 2018 Mar 1
21 29358323 Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2. 2018 Mar 9 1
22 29476987 Isoprenoids and tau pathology in sporadic Alzheimer's disease. 2018 May 2
23 29858187 Targeting Rac and Cdc42 GTPases in Cancer. 2018 Jun 15 1
24 30061681 FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis. 2018 Sep 1
25 30558664 Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer. 2018 Dec 17 1
26 28202288 Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction. 2017 May 15 1
27 28498918 Expression and Activity of the Small RhoGTPase Cdc42 in Blood Cells of Older Adults Are Associated With Age and Cardiovascular Disease. 2017 Sep 1 1
28 28527113 Mutant p53 promotes cell spreading and migration via ARHGAP44. 2017 Sep 2
29 29016860 Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function. 2017 Oct 15 2
30 26542736 Guanine nucleotide induced conformational change of Cdc42 revealed by hydrogen/deuterium exchange mass spectrometry. 2016 Jan 1
31 26828437 Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor. 2016 5
32 26911374 Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression. 2016 Apr 1
33 27010858 ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells. 2016 Mar 24 1
34 27182061 Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes. 2016 May 15 1
35 27566291 Ph(-) myeloproliferative neoplasm red blood cells display deregulation of IQGAP1-Rho GTPase signaling depending on CALR/JAK2 status. 2016 Nov 1
36 27628050 Rho GTPases: Regulation and roles in cancer cell biology. 2016 Oct 2
37 27682244 Regulation of aPKC activity by Nup358 dependent SUMO modification. 2016 Sep 29 1
38 27815503 IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES. 2016 Dec 16 1
39 25497016 Cdc42 induces EGF receptor protein accumulation and promotes EGF receptor nuclear transport and cellular transformation. 2015 Jan 16 1
40 25595978 Inhibition of the small GTPase Cdc42 in regulation of epileptic-seizure in rats. 2015 Mar 19 1
41 26004135 Rich1 negatively regulates the epithelial cell cycle, proliferation and adhesion by CDC42/RAC1-PAK1-Erk1/2 pathway. 2015 Sep 1
42 26195453 A High-Throughput Assay for Rho Guanine Nucleotide Exchange Factors Based on the Transcreener GDP Assay. 2015 Dec 1
43 26375402 Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. 2015 Dec 1
44 24914801 Formins as effector proteins of Rho GTPases. 2014 1
45 25208761 Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. 2014 Sep 11 2
46 25305482 RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication. 2014 Nov 7 1
47 23181668 A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor. 2013 Feb 15 1
48 23326220 Computational analysis of Rho GTPase cycling. 2013 1
49 23384564 Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes. 2013 May 1 2
50 23475479 [Involvement of Rho proteins in G1 phase cell cycle progression]. 2013 Jan 11 1