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35191521 | ATR inhibitor AZD6738 increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting repair of DNA damage. | 2022 Apr |
1 |
| 2 |
32652867 | Knockdown of DNA-binding protein A enhances the chemotherapy sensitivity of colorectal cancer via suppressing the Wnt/β-catenin/Chk1 pathway. | 2020 Oct |
3 |
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32689938 | Transcriptomic analysis on the effects of melatonin in gastrointestinal carcinomas. | 2020 Jul 20 |
1 |
| 4 |
30111797 | Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells. | 2018 Aug 14 |
4 |
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28915668 | NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations. | 2017 Aug 22 |
3 |
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25310623 | 5‑FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53‑mutated colon cancer cells. | 2015 Jan |
4 |
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25643258 | Dual Inhibition of Cdc7 and Cdk9 by PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil. | 2015 |
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25301724 | Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. | 2014 Oct 30 |
3 |
| 9 |
23253900 | SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. | 2013 Mar-Apr |
1 |
| 10 |
21674128 | DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status. | 2011 Sep |
2 |
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19570909 | Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells. | 2009 Sep |
1 |
| 12 |
18698031 | Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil. | 2008 Aug 15 |
2 |
| 13 |
17290426 | G2/M checkpoint gene expression in developing germ cells. | 2007 May |
1 |
| 14 |
16075279 | Administration sequence-dependent antitumor effects of paclitaxel and 5-fluorouracil in the human gastric cancer cell line MKN45. | 2006 Feb |
1 |
| 15 |
16928813 | Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy. | 2006 Aug |
1 |
| 16 |
15608676 | A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation. | 2005 Feb 17 |
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