pyrimidine

checkpoint kinase 1 ; Homo sapiens







5 Article(s)
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1 32034120 Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors. 2020 Feb 7 2
2 33176741 5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts. 2020 Nov 11 1
3 31431503 The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion. 2019 Oct 18 1
4 27383768 A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation. 2016 Aug 15 1
5 22246285 Structural requirements of pyrimidine, thienopyridine and ureido thiophene carboxamide-based inhibitors of the checkpoint kinase 1: QSAR, docking, molecular dynamics analysis. 2012 Jul 1