Celecoxib

pyruvate dehydrogenase kinase 1 ; Homo sapiens







10 Article(s)
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1 33152664 Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy. 2021 Jan 1
2 18413793 Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor. 2008 Apr 1
3 17673571 2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase. 2007 Nov 1
4 16455452 A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth. 2006 Feb 1
5 16497409 Cytotoxicity of a non-cyclooxygenase-2 inhibitory derivative of celecoxib in non-small-cell lung cancer A549 cells. 2006 Apr 1
6 16887935 Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor. 2006 Nov 1
7 16060857 Neutrophil gelatinase-associated lipocalin as a survival factor. 2005 Oct 15 2
8 14973075 3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. 2004 Feb 15 2
9 15205346 From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. 2004 Jun 15 9
10 12000750 Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. 2002 Aug 2 7