Oligonucleotides

toll like receptor 9 ; Homo sapiens







107 Article(s)
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Pub. Year
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1 32827132 CpG Oligonucleotides as Vaccine Adjuvants. 2021 2
2 33783302 CpG-Adjuvanted Hepatitis B Vaccine (HEPLISAV-B®) Update. 2021 May 1
3 31470365 Role of Ca2+ in toll-like receptor 9 activation in human plasmacytoid dendritic cells. 2020 Jan 1
4 31630153 The TLR9 Agonist Cobitolimod Induces IL10-Producing Wound Healing Macrophages and Regulatory T Cells in Ulcerative Colitis. 2020 May 21 2
5 31805184 Myeloid cell-targeted miR-146a mimic inhibits NF-κB-driven inflammation and leukemia progression in vivo. 2020 Jan 16 1
6 33031757 Cobitolimod for moderate-to-severe, left-sided ulcerative colitis (CONDUCT): a phase 2b randomised, double-blind, placebo-controlled, dose-ranging induction trial. 2020 Dec 2
7 31068803 Oligonucleotides-A Novel Promising Therapeutic Option for IBD. 2019 1
8 31335975 CD93 is a cell surface lectin receptor involved in the control of the inflammatory response stimulated by exogenous DNA. 2019 Oct 1
9 29423660 Targeting Suppressive Oligonucleotide to Lymph Nodes Inhibits Toll-like Receptor-9-Mediated Activation of Adaptive Immunity. 2018 Feb 8 1
10 29439958 Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells. 2018 Apr 2
11 29526082 Immunostimulatory CpG on Carbon Nanotubes Selectively Inhibits Migration of Brain Tumor Cells. 2018 May 16 2
12 29717061 The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome. 2018 May 1 2
13 30337279 STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers. 2018 Dec 1 2
14 27718183 Development of the CpG Adjuvant 1018: A Case Study. 2017 1
15 28214929 Myeloid cells as a target for oligonucleotide therapeutics: turning obstacles into opportunities. 2017 Aug 4
16 28500073 FcγRIIIa Signaling Modulates Endosomal TLR Responses in Human CD4+ T Cells. 2017 Jun 15 1
17 27572942 Ameliorating Active Ulcerative Colitis via an Orally Available Toll-Like Receptor-9 Modifier: A Prospective Open-Label, Multicenter Phase II Trial. 2016 Nov 1
18 27579996 Design of Polyelectrolyte Multilayers to Promote Immunological Tolerance. 2016 Oct 25 2
19 25627002 Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease. 2015 Apr 1
20 25695778 Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. 2015 1
21 25855902 Toll-like receptor 9 signaling regulates tissue factor and tissue factor pathway inhibitor expression in human endothelial cells and coagulation in mice. 2015 Jun 3
22 26034339 Optically Triggered Immune Response through Photocaged Oligonucleotides. 2015 Jun 3 1
23 26152778 Interferon-α curbs production of interleukin-22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi. 2015 Oct 1
24 26451303 Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment. 2015 Oct 2
25 24308579 Recent progress concerning CpG DNA and its use as a vaccine adjuvant. 2014 Feb 2
26 24466313 Toll-like receptor 9 signaling delays neutrophil apoptosis by increasing transcription of Mcl-1. 2014 1
27 24619691 TLR-9 agonist immunostimulatory sequence adjuvants linked to cancer antigens. 2014 2
28 24647486 Functional expression of TLR9 in esophageal cancer. 2014 May 1
29 24975812 Clinical evaluation of CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases and cancer. 2014 Nov 12 1
30 24995383 Oligonucleotides designed to inhibit TLR9 block Herpes simplex virus type 1 infection at multiple steps. 2014 Sep 7
31 25441838 Could DNA-reactive B lymphocytes be activated through HIV-1 DNA-stimulation involving BCR/TLR-9 pathway to yield antibodies targeting viral DNA? 2014 Dec 1
32 28548068 Toll-Like Receptor 9 Agonists for Cancer Therapy. 2014 Aug 4 1
33 23396449 Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9. 2013 Apr 1 1
34 23571736 Toll-like receptor 9 agonist IMO cooperates with everolimus in renal cell carcinoma by interfering with tumour growth and angiogenesis. 2013 Apr 30 1
35 23616277 IRF-5 and NF-κB p50 co-regulate IFN-β and IL-6 expression in TLR9-stimulated human plasmacytoid dendritic cells. 2013 Jul 1
36 23686399 Primary blood neutrophils express a functional cell surface Toll-like receptor 9. 2013 Aug 5
37 23755833 Selectively targeting the toll-like receptor 9 (TLR9)--IRF 7 signaling pathway by polymer blend particles. 2013 Sep 1
38 23864774 Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: clinico-pathogenic aspects. 2013 Jul 14 1
39 21812536 Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia. 2012 Feb 1
40 22086297 Modulating toll-like receptor 7 and 9 responses as therapy for allergy and autoimmunity. 2012 Feb 1
41 22613717 Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells. 2012 Jul 13 1
42 22617774 HMGB1 was a pivotal synergistic effecor for CpG oligonucleotide to enhance the progression of human lung cancer cells. 2012 Jul 1
43 22675199 Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA. 2012 Jul 1 1
44 22708497 The counter regulatory response induced by CpG oligonucleotides prevents bleomycin induced pneumopathy. 2012 Jun 18 1
45 22822061 Leucine-rich repeat 11 of Toll-like receptor 9 can tightly bind to CpG-containing oligodeoxynucleotides, and the positively charged residues are critical for the high affinity. 2012 Aug 31 1
46 22934281 Effect of CpG ODN on monocytic myeloid derived suppressor cells. 2012 Aug 1 1
47 22941279 Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides. 2012 Oct 21 2
48 23140401 Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity. 2012 Nov 11 1
49 23238459 Synthetic immunostimulatory oligonucleotides in experimental and clinical practice. 2012 1
50 21093498 Adjuvating the adjuvant: facilitated delivery of an immunomodulatory oligonucleotide to TLR9 by a cationic antimicrobial peptide in dendritic cells. 2011 Jan 10 1